II. Physiology

  1. Associated with Hair Follicles in hair covered areas
  2. Independent of Hair Follicles at mucosal margins
    1. Lips
    2. Eyelids
    3. Penis
    4. Labia Minora
    5. Nipples
  3. Secretes oily substance (sebum) onto hair
  4. Sebum acts to waterproof hair and skin

III. Histology

  1. Acinus produces sebum
    1. Round cells with lipid-filled vacuoles
    2. Secretion of sebum known as Holocrine Secretion
  2. Branched acini join at short duct
  3. Duct empties into Hair Follicle
  4. Images
    1. dermHairFollicleGrayBB944.gifLewis (1918) Gray's Anatomy 20th ed (in public domain at Yahoo or BartleBy)

IV. Sebaceous Gland Conditions

V. References

  1. Wheater (1987) Functional Histology, p. 130-2
  2. Murphy in Cotran (1989) Robbins Pathology, p. 1277-8

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Ontology: Sebaceous Glands (C0036505)

Definition (NCI_CDISC) Small glands located within the epidermis, and associated with the hair follicle, that produce and secrete an oily substance that lubricates the skin and hair. (NCI)
Definition (NCI) Small glands located within the epidermis, and associated with the hair follicle, that produce and secrete an oily substance that lubricates the skin and hair.
Definition (MSH) Small, sacculated organs found within the DERMIS. Each gland has a single duct that emerges from a cluster of oval alveoli. Each alveolus consists of a transparent BASEMENT MEMBRANE enclosing epithelial cells. The ducts from most sebaceous glands open into a HAIR FOLLICLE, but some open on the general surface of the SKIN. Sebaceous glands secrete SEBUM.
Definition (CSP) small, sacculated organs found within the dermis which secrete sebum; ducts from most sebaceous glands open into a hair follicle but some open on the general surface of the skin.
Concepts Body Part, Organ, or Organ Component (T023)
MSH D012627
SnomedCT 1028005
English Gland, Sebaceous, Glands, Sebaceous, sebaceous gland, Glandula sebacea, Glandulae sebaceae, Sebaceous glands, Glands of Zeis, Sebaceous glands set, Set of sebaceous glands, glands sebaceous, sebaceous glands, gland sebaceous, GLAND, SEBACEOUS, SEBACEOUS GLAND, Sebaceous gland, Sebaceous gland structure (body structure), Sebaceous gland structure, Sebaceous Glands, Sebaceous Gland
French Glande sébacée, Glandes sébacées
Swedish Talgkörtlar
Czech mazové žlázy
Finnish Talirauhaset
Russian SAL'NYE ZHELEZY, САЛЬНЫЕ ЖЕЛЕЗЫ
Croatian ŽLIJEZDE LOJNICE
Latvian Not Translated[Sebaceous Glands]
Polish Gruczoły łojowe
Spanish estructura de glándula sebácea (estructura corporal), estructura de la glándula sebácea, estructura de glándula sebácea, estructura de la glándula sebácea (estructura corporal), glándula sebácea, Glándulas Sebáceas
Norwegian Glandulae sebaceae, Talgkjertler
German Glandulae sebaceae, Talgdrüsen
Italian Ghiandole sebacee
Dutch Glandulae sebaceae, Talgklier, Talgklieren
Portuguese Glândulas Sebáceas

Ontology: Sebum (C0036511)

Definition (NCI_CDISC) A thick, oily substance produced by the sebaceous glands located in the dermis. (NCI)
Definition (NCI) A thick, oily substance produced by the sebaceous glands located in the dermis.
Definition (NCI_NCI-GLOSS) An oily substance produced by certain glands in the skin.
Definition (MSH) The oily substance secreted by SEBACEOUS GLANDS. It is composed of KERATIN, fat, and cellular debris.
Concepts Body Substance (T031)
MSH D012629
SnomedCT 51280008
English Sebums, sebum, Portion of sebum, SEBUM, Sebum (substance), Sebum
Swedish Talg
Spanish sebo, sebo (sustancia), secreción sebácea (sustancia), secreción sebácea, Sebo
Czech sebum
Finnish Tali
Russian KOZHNOE SALO, КОЖНОЕ САЛО
Polish Łój
French Sébum
German Sebum, Talg
Italian Sebo
Dutch Huidsmeer, Sebum, Talg
Portuguese Sebo