II. History

  1. First described by German physician in 1897

III. Pathophysiology

  1. Complication of untreated Ventricular Septal Defect
  2. Findings
    1. Ventricular Septal Defect
    2. Pulmonary Hypertension
    3. Right to left shunt
    4. Overriding aorta variably present

IV. Symptoms

V. Signs

  1. Cyanosis
  2. Systolic Murmur in the 4th left intercostal interspace
  3. Accentuated P2 of the Second Heart Sound
  4. Finger Clubbing
  5. Accentuated precordial thrust of right ventricle

VI. Diagnostics: Electrocardiogram

  1. Right Axis Deviation
  2. Ventricular Hypertrophy

VII. Labs

  1. Hemoglobin increased (Erythrocytosis)

VIII. Complications

  1. Right Ventricular failure
  2. Tricuspid regurgitation
  3. Cerebrovascular Accident
  4. Renal Failure
  5. Arrhythmia
  6. Iron Deficiency Anemia

IX. References

  1. Saenz (1999) Am Fam Physician 59(7):1857-66 [PubMed]
  2. Cyran (1998) PREP review lecture, October, Phoenix
  3. Merenstein (1994) Pediatrics, Lange

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Ontology: Eisenmenger Complex (C0013743)

Definition (MSHCZE) Soubor příznaků vrozené srdeční vady, při které se defekt komorového septa (VSD) sdružuje s dextropozicí aorty (nasedá nad defektem). Vada je cyanotická a označuje se někdy jako prostá transpozice s nasedající aortou. Plný obraz klasické Eisenmengerovy tetralogie se objeví po rozvoji plicní hypertenze s hypertrofií pravé komory a obrácením zkratu. (cit. Velký lékařský slovník online, 2013 http://lekarske.slovniky.cz/ )
Definition (NCI) A syndrome characterized by the reversal of a septal defect-associated left-to-right shunt due to the resulting secondary pulmonary hypertension. The presence of the pulmonary hypertension causes increased pressure in the right heart chambers resulting in the reversal of the shunt into a right-to-left shunt. Signs and symptoms include cyanosis, pulmonary hypertension, heart failure, and high red blood cell count.
Definition (MSH) A condition associated with VENTRICULAR SEPTAL DEFECT and other congenital heart defects that allow the mixing of pulmonary and systemic circulation, increase blood flow into the lung, and subsequent responses to low oxygen in blood. This complex is characterized by progressive PULMONARY HYPERTENSION; HYPERTROPHY of the RIGHT VENTRICLE; CYANOSIS; and ERYTHROCYTOSIS.
Concepts Disease or Syndrome (T047) , Congenital Abnormality (T019)
MSH D004541
ICD10 I27.89 , Q21.8
SnomedCT 83130006, 445928005, 204311009, 270547008, 156914003
English Complex, Eisenmenger, Eisenmenger Complex, Eisenmenger Syndrome, Eisenmenger's Complex, Eisenmenger's Syndrome, Eisenmengers Complex, Eisenmengers Syndrome, Syndrome, Eisenmenger, Complex, Eisenmenger's, Syndrome, Eisenmenger's, Eisenmenger's syndrome (diagnosis), Eisenmenger defect, Eisenmenger Complex [Disease/Finding], eisenmenger syndrome, eisenmenger's complex, eisenmenger's syndrome, eisenmengers complex, eisenmenger complex, eisenmengers syndrome, Eisenmenger's syndrome (disorder), Eisenmenger complex, Eisenmenger's syndrome, Eisenmenger's complex, Eisenmenger syndrome, Eisenmenger's complex (disorder), Eisenmenger's defect, Eisenmenger's defect (disorder), Eisenmenger; complex, Eisenmenger; defect, Eisenmenger, complex; Eisenmenger, defect; Eisenmenger, Eisenmenger's defect or complex
Swedish Eisenmengers komplex
Japanese アイゼンメンゲルショウコウグン, Eisenmenger症候群, Eisenmenger複合, アイゼンメンゲルコンプレックス, アイゼンメンゲル症候群, アイゼンメンゲル複合, アイゼンメンガー複合体
Finnish Eisenmengerin oireyhtymä
Russian EIZENMENGERA SINDROM, EIZENMENGERA KOMPLEKS, ЭЙЗЕНМЕНГЕРА КОМПЛЕКС, ЭЙЗЕНМЕНГЕРА СИНДРОМ
Italian Sindrome di Eisenmenger, Complesso di Eisenmenger
Polish Zespół Eisenmengera
Spanish complejo de Eisenmenger, síndrome de Eisenmenger, síndrome de Eisenmenger (trastorno), complejo de Eisenmenger (trastorno), defecto de Eisenmenger (trastorno), defecto de Eisenmenger, Complejo de Eisenmenger, Síndrome de Eisenmenger
Hungarian Eisenmenger-syndroma
Norwegian Eisenmengers syndrom
Czech plicní vaskulární nemoc, Eisenmengerův komplex, Eisenmengerův syndrom
Dutch Eisenmenger; complex, Eisenmenger; defect, complex; Eisenmenger, defect; Eisenmenger, Eisenmenger-complex, Eisenmenger-syndroom, Syndroom, Eisenmenger-
Portuguese Síndroma de Eisenmenger, Complexo de Eisenmenger, Síndrome de Eisenmenger
French Syndrome d'Eisenmenger, Complexe d'Eisenmenger
German Eisenmenger-Komplex, Eisenmenger-Syndrom