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Erectile Dysfunction CausesAka: Impotence Causes

Endocrine Causes
1. Diabetes Mellitus (most common)
  1. Impotence occurs in 50% of men with Diabetes Mellitus
  2. Abnormal glucose tolerance in 15% men with Impotence
2. Hypogonadism (5% of Impotence cases)
3. Hyperprolactinemia (Prolactinoma)
4. Hypothyroidism (6% of Impotence cases)
5. Hyperthyroidism
6. Cushing's Syndrome
Vascular Causes
1. Peripheral Vascular Disease
2. Chronic Renal Failure
Neurologic disease causes
1. Multiple Sclerosis
2. Alzheimer's Disease
3. Parkinson's Disease
4. Spinal Cord Injury (50% Impotence risk)
5. Pelvic irradiation
6. Pelvic Surgery
  1. Simple Prostatectomy: 10% Impotence risk
  2. Radical Prostatectomy: 40% Impotence risk
Medications
1. See Medication Causes of Impotence
Habit Related Causes
1. Substance Abuse
  1. Alcoholism (associated with Hypogonadism)
  2. Anabolic Steroids
  3. Heroin
  4. Marijuana
2. Tobacco Abuse
  1. Penile artery clot in 72% of men with 20 pack years
Miscellaneous Causes
1. Obesity
2. Peyronie's Disease
3. Psychogenic causes (20% of Impotence cases)

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 3/22/2010. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.