Rheumatology Book

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Muscle Weakness

Aka: Muscle Weakness
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  1. Evaluation
    1. Distinguish weakness from Fatigue and Asthenia
      1. Asthenia is exhaustion without weakness
      2. Fatigue is inability to perform task repeatedly
      3. Weakness is inability to perform task initially
    2. Determine distribution
      1. Unilateral, focal weakness
        1. Mononeuropathy
        2. Multiple Sclerosis
        3. Cerebrovascular Accident (CVA)
      2. Symmetric proximal weakness
        1. Myopathy
      3. Symmetric distal weakness
        1. Polyneuropathy
        2. Amyotrophic Lateral Sclerosis
        3. Guillain-Barre Syndrome
        4. Myopathy less commonly effects distal muscles
          1. Statins, Alcohol may effect distal and proximal
          2. Inclusion body Myositis
          3. Myotonic dystrophy
    3. Consider specific causes
      1. See Muscle Weakness Causes
      2. See Neuropathy
      3. See Toxic Myopathy
  2. Diagnostic evaluation based on category
    1. See Neuropathy
    2. Myopathy (see also Polymyositis)
      1. Creatine Kinase (CPK)
      2. Erythrocyte Sedimentation Rate
      3. Serum chemistry (e.g. Chem 8)
        1. Electrolytes Glucose, calcium, Magnesium, phosphate
      4. Thyroid Stimulating Hormone (TSH)
      5. Other tests as indicated
        1. 24-hour urine cortisol
        2. Growth Hormone
        3. Antinuclear Antibody
      6. Definitive testing
        1. Electromyogram
        2. Muscle Biopsy

Muscle Weakness (C0151786)

Definition (MSH) A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)
Definition (NCI) A reduction in the strength of one or more muscles.
Concepts Finding (T033)
MSH D018908
SnomedCT 26544005
English MUSCLE WEAKNESS, MUSCULAR WEAKNESS, WEAKNESS MUSCLE, Muscle Weaknesses, Muscular Weakness, Muscular Weaknesses, Weakness, Muscle, Weakness, Muscular, Weaknesses, Muscle, Weaknesses, Muscular, Decreased muscle strength, Diminished muscle strength, Muscle Weakness, decreased muscle strength, muscle weakness (symptom), muscle weakness, Muscle weakness NOS, Weakness muscle, WEAKNESS, MUSCULAR, Muscle Weakness [Disease/Finding], muscle weaknesses, muscular weakness, Weakness;muscle(s), Muscular weakness, Muscle weakness, Muscle strength reduced, Muscle weakness (finding), muscle; weakness
Spanish DEBILIDAD MUSCULAR, Debilidad muscular, Debilidad muscular NEOM, debilidad muscular, debilidad muscular (hallazgo), paresia, paresia (hallazgo), fuerza muscular disminuida, Pérdida de fuerza muscular, Debilidad Muscular
Dutch spier zwakte, spierzwakte NAO, zwakte van spier, spier; zwak, spierzwakte, Spierzwakte, Zwakte, spier-
French Faiblesse de muscle, Faiblesse musculaire SAI, FAIBLESSE MUSCULAIRE, Faiblesse musculaire, Faiblesse du muscle
German Muskelschwaechen, Schwaeche Muskel, Muskelschwaeche NNB, MUSKELSCHWAECHE, Muskelschwaeche, Muskelschwäche
Italian Debolezza muscolare NAS, Debolezza muscolare
Portuguese Fraqueza do músculo, Paresia NE, FRAQUEZA MUSCULAR, Fraqueza muscular, Debilidade Muscular
Japanese 筋力低下ＮＯＳ, ｷﾝﾘｮｸﾃｲｶNOS, ｷﾝﾘｮｸﾃｲｶ, 筋力低下
Swedish Muskelsvaghet
Czech svaly - slabost, Svalová slabost, Slabost svalu, Svalová slabost NOS
Finnish Lihasheikkous
Russian MYSHECHNAIA SLABOST', МЫШЕЧНАЯ СЛАБОСТЬ
Polish Osłabienie mięśni, Słabość mięśni
Hungarian Izomgyengeség k.m.n., Izomgyengeség
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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