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Rheumatoid Arthritis Articular Signs

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  1. See Also
    1. Rheumatoid Arthritis
    2. Rheumatoid Arthritis Diagnosis
    3. Rheumatoid Arthritis Extra-articular Signs
    4. Felty's Syndrome
    5. Rheumatoid Arthritis Management
    6. Rheumatoid Arthritis Antiinflammatory Medications
    7. Rheumatoid Arthritis Remittive Agents
  2. General Joint Changes
    1. Joints affected have high synovium to cartilage ratio
    2. Synovium is initial site for joint destruction
      1. Pannus formation (Synovial Proliferation)
      2. Pannus grows to engulf the surrounding tissues
    3. Soft Tissue Destruction
      1. Results in laxity of tendons and ligaments
    4. Juxtaarticular bone Erosion is ultimate RA course
    5. Inflammation of affected joints
      1. Boggy, tender, and warm
      2. Joints arenot erythematous
      3. Joints held in flexion to decrease pain
      4. Weakness at affected joints out of proportion to pain
  3. Spared joints
    1. Thoracic and lumbar spine
    2. Sacroiliac joints
    3. Finger DIP joints
    4. Toe IP joints
  4. Hand Involvement
    1. Wrists are almost always affected
    2. Proximal Interphalangeal Joint (PIP) swelling
      1. Fusiform or spindle-shaped appearance of fingers
    3. Metacarpophalangeal joint (MCP) swelling
    4. Sparing of Distal Interphalangeal Joint (DIP) joint
    5. Ulnar deviation of fingers
      1. Predisposes to palmar subluxation proximal phalanges
    6. Loss of hand strength
    7. Loss of pinch strength
  5. Wrist Involvement
    1. Painless ulnar swelling in styloid area (Early change)
    2. Reduced range of motion
      1. Normal ROM: 180 degrees palmar to dorsiflexion
    3. Erosion of Pisiform and Triquetrum
    4. Median Nerve compression at volar wrist
      1. Carpal Tunnel Syndrome results
  6. Elbow Involvement
    1. Flexion contractures and swelling at elbow
    2. Para-Olecranon groove bony destruction
    3. Predisposition to Elbow Dislocation
  7. Shoulder Involvement
    1. Limited Range of Motion
    2. Tenderness below and lateral to coracoid process
    3. Rupture of joint capsule and subluxation of humerus
  8. Neck Involvement
    1. Swan Neck deformity
    2. Predisposition to atlantoaxial subluxation
      1. Spinal cord compression
      2. Vertebrobasilar Insufficiency
        1. Syncope on downward gaze
    3. Limited Range of Motion
      1. Rotary ROM more affected than flexion and extension
    4. Occipital Headache
  9. Hip Involvement
    1. Abnormal Gait and limited joint motion
    2. Discomfort in the groin
      1. Pain may be referred to buttock or back
  10. Knee Involvement
    1. Synovial hypertrophy and effusion
  11. Foot and Ankle Involvement
    1. Cocking up of toes
      1. Subluxation of metatarsal heads
      2. Ultimately take on claw-like appearance
    2. Fibular deviation of 1st to 4th toes
    3. XRAY changes (may appear before hand and wrist)
      1. Fifth metatarsal medial and lateral MTP
      2. Medial first to fourth MTP joints
      3. Great toe (first toe) ITP joint
    4. Retrocalcaneal Bursitis

Rheumatoid Arthritis (C0003873)

Definition (MSH)A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
Definition (CSP)chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures; etiology is unknown, but autoimmune mechanisms have been implicated.
Definition (NCI)A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
ConceptsDisease or Syndrome (T047)
ICD9714.0, 714.0
MSHD001172
EnglishARTHRITIS RHEUMATOID, Atrophic arthritis, Chronic rheumatic arthritis, RA, RA - Rheumatoid arthritis, RhA - Rheumatoid arthritis, Rheumatic gout, Rheumatoid Arthritis, Rheumatoid disease
Spanishartritis atrofica, artritis reumatica cronica, artritis reumatoide, gota reumatica
Parent ConceptsInflammatory polyarthritis (C1692871), [X]Inflammatory polyarthropathies (C1692324), Arthritis (C0003864), Autoimmune Diseases (C0004364), Arthropathies NOS (C0022408), COLLAGEN VASCULAR DISEASE (C0262428), Multiple Organ Syndromes NEC (C0549513), Rheumatoid arthritis and other inflammatory polyarthropathies (C0157913), Rheumatism (C0035435), Rheumatologic Disorder (C0748408), Rheumatoid Arthritis (C0003873), Arthropathy associated with a hypersensitivity reaction (C0263730), Duplicate concept (C1274013), Delayed hypersensitivity disorder (C1960693)
SourcesAIR, AOD, COSTAR, CSP, CST, DXP, ICD9CM, MEDLINEPLUS, MSH, MTH, MTHICD9, NCI, NDFRT, OMIM, QMR, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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