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Antiphospholipid Antibody

Aka: Antiphospholipid Antibody, aPL Antibody, Antiphospholipid Antibodies

See Also
1. Antinuclear Antibody
Mechanism
1. IgM, IgG, or IgA binding to cell-membrane constituents
Screening
1. Measured by enzyme-linked immunosorbent assay
Types of Antiphospholipid Antibodies
1. Anticardiolipin (ACL)
2. Lupus Anticoagulant
  1. Prolongs Partial Thromboplastin Time (PTT)
  2. Prolongs Russell viper venom time
3. VDRL false positive
Condition associated with APL elevations (>3 SD)
1. Antiphospholipid Antibody Syndrome
Indications fo APL testing
1. Connective Tissue disease with clotting disorder
2. Recurrent thrombosis without obvious cause
  1. See Hypercoagulability

Family Practice Notebook

Patients should address specific medical concerns with their physicians.

Although access to this page is not restricted, the information found here is intended for use by medical providers.

This page was written by Scott Moses, MD, last revised on 10/21/2007 and last published on 2/5/2012.

This is one of 5663 pages in the Family Practice Notebook