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Anti-ribonucleoprotein AntibodyAka: Anti-RNP Antibody, Anti-U1 snRNP Antibody, Ribonucleoprotein Antibody, Anti-RNP, Anti-U1 snRNP

See Also
1. Antinuclear Antibody
Negative
1. Normal
Positive (percentage refers to sensitivity)
1. Systemic Lupus Erythematosus (30-40%)
  1. Correlates with disease activity
2. Rheumatoid Arthritis (10%)
3. Sjogren's Syndrome (15%)
4. Mixed Connective Tissue Disease (95%)
5. Systemic Sclerosis (30%)
6. Drug Induced Lupus (<5%)
References
1. Gladman in Klippel (1997) Rheumatic Diseases p. 255-6
2. Peng in Ruddy (2001) Kelley's Rheumatology, p. 161-72
3. Callegari (1995) Postgrad Med 97(4):65
4. Lane (2002) Am Fam Physician 65(6):1073

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.