Rheumatology Book

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Hypertrophic OsteoarthropathyAka: Osteoarthropathy, Acropachy

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  1. See Also
    1. Clubbing
  2. Definition
    1. Excess skin and bone proliferation at distal extremity
  3. Pathophysiology
    1. Large platelets accumulate in distal extremities
    2. Fibroblast growth factors released
    3. Results in edema and excess collagen deposition
    4. Increased bone formation distally also occurs
  4. Causes
    1. See Hypertrophic Osteoarthropathy Causes
  5. Symptoms
    1. Often asymptomatic
    2. Deep bone pain at distal extremities (usually legs)
  6. Signs
    1. Digital Clubbing
    2. Bone thickening of wrists and ankles
  7. References
    1. Klippel (1997) Primer Rheumatic Diseases, p. 370-1

Osteoarthropathy, Secondary Hypertrophic (C0029412)

Definition (MSH)Symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement. It is often secondary to chronic conditions of the lungs and heart. (Dorland, 27th ed)
ConceptsDisease or Syndrome (T047)
ICD9731.2, 731.2
MSHD010005
EnglishAcropachy, Bamberger-Marie disease, HPOA - Hypertrophic pulmonary osteoarthropathy, HYPERTROPH OSTEOARTHROP, HYPERTROPHIC OSTEOARTHROPATHY SECOND, Hypertrophic pulmonary osteoarthropathy, MARIE BAMBERGER DIS, Marie Bamberger disease, Marie-Bamberger Disease, OSTEOARTHROPATHY SECOND HYPERTROPHIC, Pachydermoperiostitis acquired, SECOND HYPERTROPHIC OSTEOARTHROPATHY, Secondary Hypertrophic Osteoarthropathies, Secondary hypertrophic osteoarthropathy
Spanishacropaquia, enfermedad de Bamberger - Marie, enfermedad de Bamberger-Marie, enfermedad de Marie Bamberger, osteoartropatia hipertrofiante pneumica, osteoartropatia hipertrofica secundaria, osteoartropatia pulmonar hipertrofica, paquidermoperiostitis adquirida
Parent ConceptsOsteitis deformans and osteopathies associated with other disorders classified elsewhere (C0029402), Bone Diseases (C0005940), Arthropathies NOS (C0022408), Arthropathy associated with respiratory disorder (C0263727), Ambiguous concept (C1274012)
SourcesCOSTAR, CSP, ICD9CM, MSH, MTH, MTHICD9, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Hypertrophic osteoarthropathy (C0178703)

Definition (CSP)two types, primary type is a condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, seborrhea, hyperhidrosis, periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet, it is more prevalent in the male; secondary type is a condition with symmetrical osteitis of the four limbs, chiefly localized to the phalanges and the terminal epiphyses of the long bones of the forearm and leg, sometimes extending to the proximal ends of the limbs and the flat bones, and accompanied by dorsal kyphosis and joint involvement, and is often secondary to chronic conditions of the lungs and heart.
ConceptsDisease or Syndrome (T047)
EnglishHOA - Hypertrophic osteoarthropathy, Hypertrophic osteoarthropathy
Spanishosteoartropatia hipertrofica
Parent ConceptsHypertrophy (C0020564), Arthropathies NOS (C0022408), Bone Diseases (C0005940), Duplicate concept (C1274013)
SourcesCSP, DXP, QMR, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Disorder of skeletal system (C0263661)

Definition (CSP)disorders of the skeletal system; includes both bone and cartilage.
ConceptsDisease or Syndrome (T047)
EnglishBONE/JOINT DISORDERS, Disease of bone AND/OR joint, Disease of skeletal system, Disorder of skeletal system, osteoarthropathy, skeletal disorder
Spanishenfermedad de hueso Y/O de articulacion, enfermedad del sistema esqueletico, enfermedad osea Y/O articular, osteoartropatia, trastorno del sistema esqueletico
Parent ConceptsDegenerative polyarthritis (C0029408), Musculoskeletal Diseases (C0026857), NONSPECIFIC DISORDERS (C0549601)
SourcesAOD, CSP, CST, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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