Nephrology Book

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Hypoosmolar Hyponatremia

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  1. See Also
    1. Hyponatremia
  2. Definition
    1. Hyponatremia with Measured Serum Osmolality <280 mOsm
  3. Approach
    1. Assess Extracellular Fluid Volume
      1. Orthostatic Blood Pressure and Pulse
      2. Skin turgor
      3. Edema
    2. What is Patient's Volume Status?
      1. Hypervolemic Hypoosmolar Hyponatremia
      2. Non-Hypervolemic (Iso- or Hypovolemic)
        1. Difficult to distinguish Iso- from Hypovolemic
        2. Hypovolemic Hypoosmolar Hyponatremia
        3. Isovolemic Hypoosmolar Hyponatremia
    3. Obtain Urine Sodium
      1. Differentiate renal from extrarenal cause
  4. Management
    1. See Hyponatremia Management
    2. See specific protocols based on fluid status above
  5. References
    1. Kone in Tisher (1993) Nephrology, p. 87-100
    2. Levinsky in Wilson (1991) Harrison's IM, p. 281-84
    3. Rose (1989) Acid-Base and Electrolytes, p. 601-38

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