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Hyperosmolar Hyponatremia

See Also
1. Hyponatremia
Definition
1. Hyponatremia with Measured Serum Osmolality >300 mOsm
Causes
1. Hypertonic infusion
  1. Glucose
  2. Mannitol
  3. Glycine
2. Hyperglycemia
  1. Associated Conditions
    1. Diabetic Ketoacidosis
    2. Hyperosmolar Hyperglycemic Nonketotic Coma
  2. Calculation
    1. Sodium falls 1.6 meq/L per 100 mg/dl glucose rise
References
1. Kone in Tisher (1993) Nephrology, p. 87-100
2. Levinsky in Wilson (1991) Harrison's IM, p. 281-84
3. Rose (1989) Acid-Base and Electrolytes, p. 601-38

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.