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HyperphosphatemiaAka: High Serum Phosphorus
- Causes
- Renal Failure
- Dehydration
- Addison's Disease
- Hypervitaminosis D
- Hypoparathyroid
- Magnesium deficiency
- Milk-Alkali Syndrome
- Transfusions
- Hemolysis
- Sarcoidosis
- Bone metastases
- Myelogenous Leukemia
- Evaluation: Renal Failure
- Chronic Renal Failure
- Increased phosphate when GFR falls below 20 ml/min
- Usually Phosphate in 5-10 mg/dl range
- Acute Renal Failure
- Especially in oliguric or hypercatabolic forms
- Highest in:
- Myoglobinuric Acute Tubular Necrosis
- Surgery
- Trauma
- Chronic Renal Failure
- Evaluation: Normal Renal Function
- Check Urinary phosphate excretion (Urine pHosphate)
- Increased Urine pHosphate: over 1500 mg/dl
- Endogenous source
- Cytotoxins
- Rhabdomyolysis
- Malignant hyperpyrexia (Fever)
- Exogenous source
- Laxative Abuse
- Enemas
- Phosphate (Oral, IV, or poisoning)
- Endogenous source
- Normal Urine pHosphate: Under 1500mg/dl
- Increased reabsorption
- Hyperparathyroidism
- Menopause
- Extracellular Fluid Volume contraction
- Tumoral calcinosis
- Increased reabsorption
- Management
- Antacid binding gel: Aluminum hydroxide (AlternaGel)
- Dose 600 mg/5 ml, 5 ml qid with meals and at bedtime
- Low Phosphate diet
- Antacid binding gel: Aluminum hydroxide (AlternaGel)
Hyperphosphatemia (C0085681) | |
|---|---|
| Definition (MSH) | A condition of abnormally high level of PHOSPHATES in the blood, usually significantly above the normal range of 0.84-1.58 mmol per liter of serum. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D054559 |
| English | HYPERPHOSPHATAEMIA, Hyperphosphatemia, Hyperphosphatemias |
| Spanish | hiperfosfatemia |
| Parent Concepts | Phosphorus Metabolism Disorders (C0031707), CALCIUM/PHOSPHATE ABNORMALITY (C0549633), Water-Electrolyte Imbalance (C0043065) |
| Sources | COSTAR, CST, DXP, MSH, MTH, NDFRT, OMIM, SCTSPA, SNOMEDCT Derived from the NIH UMLS (Unified Medical Language System) |
