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Urinary Anion GapAka: Urine Anion Gap

Indications
1. Non-Anion Gap Metabolic Acidosis
2. Distinguishes renal from extra-renal causes
Physiology: Measures unmeasured anions present in urine
1. Sulfates
2. Phosphates
3. Bicarbonates
4. Organic anions
  1. Lactate
  2. Citrate
Calculation
1. UAG = Urine Sodium + Urine Potassium - Urine Chloride
Interpretation: Normal
1. UAG = -10 to +10
Interpretation
1. Decreased Urine Anion Gap <-10
  1. Extrarenal non-Anion Gap Metabolic Acidosis
2. Increased Urine Anion Gap >+10
  1. Renal non-Anion Gap Metabolic Acidosis

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.