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Serum OsmolalityAka: Calculated Serum Osmolality, Serum Osms

See Also
1. Osmolal Gap
Normal
1. Serum Osmolality: 280-300 mOsm/(kg water)
Calculated Serum Osmolality
1. Serum Osms = 2*Na + Glu/18 + BUN/2.8 + Et/4.6 + Man/18
2. Annotation
  1. Where Na is Serum Sodium
  2. Where Glu is Serum Glucose
  3. Where BUN is Blood Urea Nitrogen
  4. Where Et is blood Alcohol level
  5. Where Man is Mannitol
Increased
1. Dehydration
2. Hypernatremia
3. Diabetes Insipidus
4. Uremia
5. Hyperglycemia
6. Mannitol
7. Toxins
  1. Ethylene Glycol
  2. Methanol
  3. Alcohol
Decreased
1. SIADH
2. Hyponatremia
3. Overhydration

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.