Nephrology Book

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Isolated Proteinuria

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  1. See Also
    1. Proteinuria
    2. Orthostatic Proteinuria
  2. Diagnosis
    1. Proteinuria <2000 mg/day without other abnormality
      1. No Hypertension
      2. No Renal Insufficiency
      3. No other urologic or renal abnormalities
    2. Diagnosis made on clinical criteria (no specific study)
  3. Labs
    1. Urine Microscopy normal
    2. Urine Protein 24 Hour collection
      1. Less than 2000 mg protein excretion per day
    3. Split 24 Hour Urine Protein collection
      1. Urine Protein >50 mg for 8 hours supine
      2. Contrast with Orthostatic Proteinuria
    4. Renal Function tests
      1. Normal Creatinine Clearance
  4. Differential Diagnosis
    1. See Proteinuria Causes
  5. Monitoring
    1. Consider Nephrology consultation
    2. Blood Pressure every 6 months
    3. Urinalysis every 6 months
    4. Creatinine Clearance every 6 months
  6. Prognosis
    1. Renal insufficiency risk: 20% in 10 years

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