Mental Health Book

Background Information

Causes

  • Major Depression Differential Diagnosis

Disease Complications

Information Resources

Management

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Major Depression Differential Diagnosis

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  1. Drug-Induced causes
    1. See Medications Predisposing to Depression
  2. Endocrine and Metabolic Causes
    1. Adrenal disease
      1. Cushing's Disease
      2. Addison's Disease
      3. Pheochromocytoma
    2. Thyroid disease
      1. Hypothyroidism
      2. Hyperthyroidism
    3. Parathyroid Disease
      1. Hypoparathyroidism
      2. Hyperparathyroidism
    4. Diabetes Mellitus
    5. Electrolyte disturbance
      1. Serum Sodium disturbance
      2. Serum Potassium disturbance
      3. Serum Calcium disturbance
      4. Hypoglycemia
    6. Carcinoid
    7. Ovarian Failure (Menopause)
    8. Testicular Failure
    9. Renal Failure or Uremia
    10. Heavy metal poisoning
  3. Infectious Disease Causes
    1. Hepatitis
    2. Herpes Simplex Virus Encephalitis
    3. HIV Infection or AIDS
    4. Mononucleosis
    5. Syphilis
    6. Tuberculosis
    7. Lyme Disease
    8. Encephalitis
    9. Influenza
  4. Hematology and Oncology Causes
    1. Pernicious Anemia
    2. Brain Tumor
    3. Pancreatic Cancer
    4. Breast Cancer
    5. Colon Cancer and other gastrointestinal cancer
    6. Gynecologic cancer
    7. Hematologic malignancy
  5. Neurologic Causes
    1. Cerebrovascular Accident (CVA)
    2. Huntington's Chorea
    3. Multiple Sclerosis
    4. Normal Pressure Hydrocephalus
    5. Parkinson's Disease
    6. Alzheimer's Disease
    7. Subdural Hematoma
    8. Narcolepsy
    9. Wilson's Disease
  6. Cardiovascular Disease
    1. Congestive Heart Failure
    2. Cerebral ischemia
    3. Cardiomyopathy
    4. Myocardial Infarction
  7. Nutritional Deficiency
    1. Macrocytic Anemia
      1. Folate Deficiency
      2. Vitamin B12 Deficiency
    2. Microcytic Anemia
      1. Iron Deficiency Anemia
    3. Other B Vitamin Deficiency
      1. Pyridoxine Deficiency (Vitamin B6)
      2. Riboflavin Deficiency (Vitamin B2)
      3. Thiamine deficiency (Vitamin B1)
  8. Miscellaneous Causes
    1. Chronic Obstructive Pulmonary Disease
    2. Hepatic failure
  9. References
    1. Citrome (1994) Postgrad Med 95(1):137
    2. Ferris (1995) Depression Primary Care, PGM, p.36-44
    3. Kuzel (1996) Postgrad Med 99(5):179

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