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  • Marijuana

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Marijuana

Aka: Marijuana, Hashish, Cannabis, THC
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  1. See Also
    1. Chemical Dependency
    2. Substance Abuse Evaluation
  2. Class
    1. Relaxant, Euphoriant, and Hallucinogen (high doses)
    2. Schedule I
  3. Pharmacokinetics
    1. THC (5-20 mg): 2-4 hour duration
    2. Long half life
  4. Street Names
    1. Pot
    2. Grass
    3. Tea
    4. Dagga
    5. Kif
    6. Joint
    7. Reefer
    8. Weed
    9. Dope
  5. Background
    1. Derived naturally from hemp, Cannabis sativa
    2. Smoked or eaten (e.g. "Hash Brownies")
  6. Pathophysiology
    1. Similar to highly addictive "hard" drugs or Opioids
      1. Results in Dopamine release
      2. Blocked by Naloxone
    2. Marijuana considered a gateway drug
      1. Use leads to Opiate Abuse
    3. References
      1. Tanda (1997) Science 276:2048-50
  7. Symptoms
    1. Acute Effects
      1. Euphoria
      2. Relaxed inhibitions
      3. Increased appetite
      4. Disoriented behavior
    2. Chronic Use: Amotivational syndrome
      1. Aimless
      2. Uncommunicative
  8. Withdrawal Symptoms
    1. Anorexia
    2. Insomnia
    3. Anxiety
    4. Depression
  9. Symptoms or Signs of Toxicity
    1. Dysphoria
    2. Tachycardia
    3. Orthostatic Hypotension
    4. May precipitate latent Schizophrenia
  10. Toxicity Management
    1. Usually no specific treatment needed
    2. Benzodiazepines for severe reactions

Marihuana (C0024808)

Definition (NCI) The dried leaves and flowering tops of the Cannabis sativa plant, or an extract from the plant. Marijuana is being studied in the treatment of nausea and vomiting caused by chemotherapy or opiate drugs, such as morphine sulfate. Marijuana is also being studied in the treatment of pain.
Definition (NCI) Any part of, or extract from, the female hemp plant Cannabis sativa. Marijuana contains cannabinoids, substances with hallucinogenic, psychoactive, and addictive properties. This agent has potential use for treating cancer pain and cachexia. (NCI04)
Definition (PDQ) Any part of, or extract from, the female hemp plant Cannabis sativa. Marijuana contains cannabinoids, substances with hallucinogenic, psychoactive, and addictive properties. This agent has potential use for treating cancer pain and cachexia. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=269131&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=269131&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26659" NCI Thesaurus)
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D002188
SnomedCT 398705004, 228997001
English Marihuana, Marijuana, cannabinols in any form, marijuana in any form, Cannabis, Marijuanas, Marihuanas, MARIJUANA [VA Product], marihuana, marihuanna, marihauna, Medicinal marijuana, marijuana, cannabis, MARIJUANA
Czech marihuana
German Marihuana
Italian Marihuana, Marijuana
French Marie-jeanne, Marijuana, Marihuana
Spanish marihuana, Marihuana
Dutch Marihuana
Portuguese Maconha
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Cannabis (C0936079)

Definition (MSH) The plant genus in the Cannabaceae plant family, Urticales order, Hamamelidae subclass. The flowering tops are called many slang terms including pot, marijuana, hashish, bhang, and ganja. The stem is an important source of hemp fiber.
Definition (CSP) plant genus of the family Cannabacae and the dried flowering tops which contain hallucinogens.
Concepts Plant (T002)
MSH D002188
SnomedCT 22924007
English Cannabis, Cannabis, NOS, Hemp Plant, cannabis, hemp plant, Cannabis (organism), Hemp (Cannabis), Cannabi, Plants, Hemp, Hemp Plants, Plant, Hemp
Swedish Kannabis
Czech Cannabis, konopí
Finnish Kannabis
Italian Pianta di canapa, Cannabis
Russian MARIKHUANA, KONOPLIA, ГАШИШ, КОНОПЛЯ, МАРИХУАНА, GASHISH
Portuguese Cânabis, Cânave, Cânhamo-da-Índia, Cannabis, Cânabe, Linho-Cânhamo
Spanish Marijuana, Cannabis, Cannabis (organismo)
Dutch Cannabis
German Cannabis
Japanese アサ属, アサ, カンナビス属, マリファナ, ハッシッシュ, 大麻
Polish Marihuana, Konopie indyjskie, Haszysz, Konopie
Croatian MARIHUANA
French Cannabis
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Tetrahydrocannabinol (C0039663)

Definition (CHV) an organic chemical extracted from Marihuana
Definition (CHV) an organic chemical extracted from Marihuana
Definition (CHV) an organic chemical extracted from Marihuana
Definition (CHV) an organic chemical extracted from Marihuana
Definition (CHV) an organic chemical extracted from Marihuana
Definition (MSH) A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. Dronabinol is a synthetic form of delta-9-THC.
Definition (NCI) A synthetic form of delta-9-tetrahydrocannabinol, a psychoactive substance found in Cannabis sativa. Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. (NCI04)
Definition (NCI) A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with cancer chemotherapy.
Definition (PDQ) A synthetic form of delta-9-tetrahydrocannabinol, a psychoactive substance found in Cannabis sativa. Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39707&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39707&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C867" NCI Thesaurus)
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D013759
SnomedCT 386846008, 72024007, 108415005, 96225007
English delta(1)-Tetrahydrocannabinol, delta(1)-THC, delta(9)-Tetrahydrocannabinol, delta(9)-THC, Dronabinol, THC, 6H-Dibenzo(b,d)pyran-1-ol, 6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-, (6aR-trans)-, 9 ene Tetrahydrocannabinol, 9-ene-Tetrahydrocannabinol, delta-9-tetrahydrocannabinol, Delta 9-Tetrahydrocannabinol, (-)-.DELTA.9-Tetrahydrocannabinol, Tetrahydrocannabinol, Synthetic delta-9-Tetrahydrocannabinol, DELTA THC 09, dronabinol, dronabinol (medication), Tetrahydrocannabinol [Chemical/Ingredient], DRONABINOL, tetrahydrocannabinol (THC), delta-9-Tetrahydrocannabinol, Dronabinol (product), Dronabinol (substance), Tetrahydrocannabinol (substance), delta-9-Tetrahydrocannabinol (substance), delta 9-tetrahydrocannabinol, tetrahydrocannabinol
Swedish Tetrahydrocannabinol
Spanish delta-9-tetrahidrocannabinol (sustancia), delta-9-tetrahidrocanabinol sintético, delta-9-tetrahidrocanabinol, delta-9-tetrahidrocannabinol, delta-9-tetrahidrocanabinol (sustancia), dronabinol (producto), dronabinol (sustancia), dronabinol, tetrahidrocanabinol (sustancia), tetrahidrocanabinol, THC, delta(9)-THC, Dronabinol, Tetrahidrocanabinol
Czech tetrahydrokanabinol
Finnish Tetrahydrokannabinoli
Italian THC, Dronabinolo, Delta(1)-THC, Delta(1)-tetraidrocannabinolo, Delta(9)-THC, Delta(9)-tetraidrocannabinolo, 9-ene-tetraidrocannabinolo, Tetraidrocannabinolo
Russian TETRAGIDROKANNABINOL, DRONABINOL, DELTA (9)-THC, THC, ДРОНАБИНОЛ, ТЕТРАГИДРОКАННАБИНОЛ
Japanese テトラヒドロカンナビノール, デルタ9THC, ドロナビノール, Δ1-3,4-trans-テトラヒドロカンナビノール
French THC (Tétrahydrocannabinol), Tétrahydrocannabinol
German DELTA THC 09, Delta(9)-THC, Dronabinol, THC, Tetrahydrocannabinol
Polish Tetrahydrokannabinol
Portuguese THC, delta (9)-THC, Dronabinol, Tetraidrocanabinol
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Hashish (C0018613)

Concepts Substance (T167)
MSH D002188
SnomedCT 228999003
English Cannabis resin - non-pharmac, hashish, Hashishs, marijuana resin, Cannabis resin - non-pharmaceutical, Marijuana resin, Marihuana resin, Cannabis resin - non-pharmaceutical (substance), Hashish
Czech hašiš
Portuguese Haxixe
Spanish Hachis, resina de Cannabis - uso no farmacéutico (sustancia), resina de Cannabis - uso no farmacéutico
German Haschisch
Italian Hashish
French Hachisch, Haschich, Hachich
Dutch Hasjiesj
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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