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BeriberiAka: Thiamine deficiency

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  1. Pathophysiology
    1. Nutritional disease results from Thiamine deficiency
  2. Causes
    1. Chronic Alcoholism
    2. Thiamine deficiency
    3. Malnutrition
    4. Diuresis
    5. Dialysis
    6. High carbohydrate intake
  3. Symptoms
    1. Weakness, irritability
    2. Nausea, Vomiting
    3. Burning feet
    4. Pruritus
  4. Signs
    1. Neurologic
      1. Tremor
      2. Diminished reflexes in lower limbs
      3. Muscle atrophy
    2. Cardiac: Congestive Heart Failure (Wet beriberi)
      1. Pedal Edema
      2. Pleural Effusions
  5. Lab
    1. Complete Blood Count
      1. Anemia
    2. Blood Thiamine lowered
    3. Erythrocyte transketolase decreased
    4. Blood pyruvate high
  6. Diagnosis
    1. Test dose of Thiamine results in no urinary excretion
  7. Radiology: Chest XRay
    1. Cardiomegaly

Beriberi (C0005122)

Definition (MSH)A disease caused by a deficiency of thiamine (vitamin B1) and characterized by polyneuritis, cardiac pathology, and edema. The epidemic form is found primarily in areas in which white (polished) rice is the staple food, as in Japan, China, the Philippines, India, and other countries of southeast Asia. (Dorland, 27th ed)
ConceptsDisease or Syndrome (T047)
ICD9265.0
MSHD001602
EnglishBeri Beri, Beri-beri, Beriberi
Spanishberiberi, hipovitaminosis B1
Parent ConceptsThiamine Deficiency (C0039841), Thiamine and niacin deficiency states (C0154239), Vitamin Deficiency (C1510471), Ambiguous concept (C1274012)
SourcesAOD, DXP, ICD9CM, MSH, NCI, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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