http://www.fpnotebook.com/
Selenium
- Potential benefits: May reduce cancer risk
- Study of 200 ug/day between 1983-1991
- Total Mortality reduced (relative risk 0.79)
- Prostate Cancer reduced (relative risk 0.37)
- Colorectal Cancer reduced (relative risk 0.42)
- Lung Cancer reduced (relative risk 0.54)
- Flawed study: Wrong study endpoints
- Needs confirmation study
- Total Mortality reduced (relative risk 0.79)
- References
- Study of 200 ug/day between 1983-1991
Selenium (C0036581) | |
|---|---|
| Definition (MSH) | An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE. |
| Definition (CSP) | element with the atomic symbol Se, atomic number 34; an essential micronutrient for mammals and other animals but toxic in large amounts; protects intracellular structures against oxidative damage. |
| Definition (NCI) | An essential dietary mineral. |
| Definition (PDQ) | A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38725&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=38725&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C825" NCI Thesaurus) |
| Definition (NCI) | An element with atomic symbol Se, atomic number 34, and atomic weight 78.96. |
| Concepts | Biologically Active Substance (T123) , Hazardous or Poisonous Substance (T131) , Element, Ion, or Isotope (T196) |
| MSH | D012643 |
| English | Se, Se - Selenium, Se element, Selenium, SELENIUM PREPARATION, Selenium product |
| Spanish | selenio |
| Parent Concepts | oxygen group elements (C0682905), Elements (C0013879), Minerals (C0026162), Chalcogens (C0206763), Antioxidants (C0003402), Trace Elements (C0040577), [TN499] ELECTROLYTES/MINERALS, OTHER (C0973657), Dermatologic Agents (C0011625), Selenium AND/OR selenium compound (C0303043), Dermatological Mitotic Inhibitors (C1579278), ELECTROLYTES/MINERALS (C1579396) |
| Sources | AOD, CSP, LCH, LNC, MSH, MTH, NCI, NDFRT, PDQ, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF Derived from the NIH UMLS (Unified Medical Language System) |
