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Drug-Drug Interactions in the Elderly

See Also
1. Polypharmacy
2. Beers List
Adverse Effect: Increased Drug effect (common)
1. Azathioprine (Imuran, Bone Marrow suppression risk)
  1. Allopurinol
2. Benzodiazepines and other sedative hypnotics (Sedation risk)
  1. Alcohol
3. Digoxin (Digoxin Toxicity risk)
  1. Diuretics
  2. Quinidine
4. Methotrexate (Bone Marrow suppression risk)
  1. Aspirin
  2. Sulfisoxazole
5. Phenytoin (Ataxia and Sedation risk)
  1. Chloramphenicol
  2. Isoniazid
  3. Phenylbutazone
6. Propranolol (Bradycardia risk)
  1. Cimetidine (Tagamet)
7. Sulfonylureas (Hypoglycemia risk)
  1. Chloramphenicol
  2. Phenylbutazone
  3. Warfarin
8. Warfarin (Bleeding risk)
  1. Aspirin
  2. Metronidazole
  3. Phenylbutazone
Adverse Effect: Decreased Drug effect (common)
1. Metformin
  1. Risperidone
2. Pioglitazone (Actos)
  1. Olanzapine (Zyprexa)
3. Prednisone
  1. Barbiturates
4. Quinidine
  1. Barbiturates
  2. Rifampin
5. Tetracycline
  1. Antacids
6. Warfarin
  1. Barbiturates
  2. Rifampin
References

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This page was written by Scott Moses, MD. This page was last revised on 3/21/2008 9:55:38 AM. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.