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Valerian RootAka: Valerian, Valepotriate, Valeric Acid

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  1. Indications
    1. Insomnia
    2. Proposed for anxiety (inconclusive data)
  2. Physiology
    1. Sedative effects related to valeric acid component
  3. Dosing: Insomnia (taken 30-120 minutes before bedtime)
    1. Best efficacy with continuous use >10-14 days
    2. Extract: 300-600 mg PO qhs
    3. Dried root: 2-3 grams in hot water 15 minutes PO qhs
  4. Efficacy: Insomnia
    1. Improved sleep latency and quality
    2. References
      1. Stevinson (2000) {a 19258} Med 1:91
      2. Ziegler (2002) Eur J Med Res 25:480
  5. Adverse effects (uncommon)
    1. Sleepiness on awakening (associated with 900 mg dose)
    2. Headache
    3. Gastrointestinal upset
    4. Withdrawal symptoms when stopped
      1. May be similar to Benzodiazepine Withdrawal
  6. References
    1. Hadley (2003) Am Fam Physician 67(8):1755

VALEPOTRIATE (C0772179)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
EnglishVALEPOTRIATE
SourcesRXNORM
Derived from the NIH UMLS (Unified Medical Language System)


Valerian extract (C0939904)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
EnglishValerian, Valerian extract, VALERIAN EXTRACT PREPARATION, Valerian preparation
Spanishextracto de valeriana, preparacion con valeriana
Parent ConceptsValerian extract (C0939904), [XX000] MISCELLANEOUS AGENTS (C0973729), Unclassified Ingredients (C1372954), Medicinal Herbs (C0025125), Plant product (C0032088), Over the counter healthfood/herbal products (C0361218), Drug allergen (C1320237), Herbal medicine agent (C1636187)
SourcesMTH, NDFRT, RXNORM, SCTSPA, SNOMEDCT, VANDF
Derived from the NIH UMLS (Unified Medical Language System)



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