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FeverfewAka: Tanacetum parthenium

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  1. Indications (Purported uses)
    1. Migraine Headache prevention
  2. Efficacy
    1. Some studies support benefit for Migraine prevention
    2. No benefit in Rheumatoid Arthritis
  3. Mechanism
    1. Inhibits prostaglandin synthesis
    2. Serotonin antagonist
    3. Inhibits platelet aggregation
  4. Dosing
    1. Standard extract 125 mg (at least 0.2% parthenolide)
  5. Adverse Effects
    1. Bleeding Diathesis due to Platelet Dysfunction
  6. Contraindications
    1. Pregnancy
      1. Feverfew may induce menstruation
    2. Concurrent anticoagulant use or peri-operative
      1. Feverfew increases bleeding risk
  7. References
    1. Shaughnessy (1997) Fam Practice Recert 19(10):53-6
    2. Zink (1998) Am Fam Physician 58(5):1133

feverfew extract (C0376266)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
EnglishFEVERFEW, feverfew extract, FEVERFEW EXTRACT PREPARATION, FEVERFEW PREPARATION
Parent Conceptsfeverfew extract (C0376266), Unclassified Ingredients (C1372954), Unclassified Ingredient Preparations (C1377282)
SourcesMTH, NDFRT, RXNORM, VANDF
Derived from the NIH UMLS (Unified Medical Language System)



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