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Feverfew

Aka: Feverfew, Tanacetum parthenium
  1. Indications (Purported uses)
    1. Migraine Headache prevention
  2. Efficacy
    1. Some studies support benefit for Migraine prevention
    2. No benefit in Rheumatoid Arthritis
  3. Mechanism
    1. Inhibits prostaglandin synthesis
    2. Serotonin antagonist
    3. Inhibits platelet aggregation
  4. Dosing
    1. Standard extract 125 mg (at least 0.2% parthenolide)
  5. Adverse Effects
    1. Bleeding Diathesis due to Platelet Dysfunction
  6. Contraindications
    1. Pregnancy
      1. Feverfew may induce menstruation
    2. Concurrent anticoagulant use or peri-operative
      1. Feverfew increases bleeding risk
  7. References
    1. Shaughnessy (1997) Fam Practice Recert 19(10):53-6
    2. Zink (1998) Am Fam Physician 58(5): 1133-40

feverfew extract (C0376266)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
English feverfew, Feverfew, Feverfew Extract, feverfew extract, FEVERFEW, feverfew (medication), FEVERFEW EXTRACT
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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