Obstetrics Book

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Teratogen ExposureAka: Teratogen

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  1. See Also
    1. Embryo Organ Development
  2. General Teratogen Susceptibility
    1. Week 0-2: Pre-organogenesis
      1. Not Sensitive to malformation
      2. Significant exposure is lethal
    2. Week 3-8: Embryonic Period
      1. Greatest sensitivity to environmental exposures
      2. Fetal mass increases 2.5 Million fold first trimester
      3. Major malformations occur
    3. Week 9-38: Fetal Period
      1. Decreasing sensitivity
      2. Functional defects and minor malformations occur
  3. Resources
    1. FDA Hotline regarding teratogen exposure information
      1. Phone: 1-800-532-3749

Teratogens (C0039536)

Definition (MSH)An agent that causes the production of physical defects in the developing embryo.
Definition (CSP)agent or factor that induces or increases the incidence of a congenital anomaly in the developing embryo.
ConceptsHazardous or Poisonous Substance (T131)
MSHD013723
Englishteratogen, Teratogenic substance, Teratogens
Spanishsubstancia teratogena, sustancia teratogena, teratogeno
Parent ConceptsPoisons (C0032346), Pharmaceutical Preparations (C0013227), Noxae (C0028470), Chemical Modifier (C1516451), Duplicate concept (C1274013)
SourcesAOD, CSP, MSH, NCI, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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