Neonatology Book

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Apnea of Prematurity

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  1. Definition
    1. Respiratory pause in a premature infant born before 37 weeks
      1. Episode lasts at least 20 seconds OR
      2. Episode accompanied by Bradycardia, Hypoxia, change in tone or atypical movements
  2. Management: Typically directed by Neonatology
    1. Methylxanthines
      1. Continue until event-free and at least 40 weeks adjusted age
    2. Apnea monitor
      1. Continue until event-free and at least 43 weeks adjusted age
  3. Course
    1. Episodes cease in most premature infants by 42-44 weeks adjusted age
  4. References

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