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Hemolytic Disease of the Newborn
Aka: Hemolytic Disease of the Newborn, Erythroblastosis Fetalis- See Also
- Pathophysiology
- Maternal Rh Sensitization
- Results in fetal Hemolytic Anemia
- Increased Unconjugated Hyperbilirubinemia
- Compensating Erythropoiesis
- Hepatosplenomegaly
- Red Blood Cell production and destruction
- Placenta enlarged
- Complications
- Fetal hydrops
- Hemolytic Anemia
- Congenital Anemia (Mild Hemolysis)
- Icterus Gravis (Severe Hemolysis)
- Kernicterus
Erythroblastosis, Fetal (C0014761) |
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| Definition (NCI) | A disorder caused when there is a Rh-factor blood-type incompatibility between the mother and fetus, and the mother's immune system forms antibodies that attack the red blood cells of her unborn child. This disorder can only occur if the mother is Rh-negative and the fetus is Rh-positive. |
| Definition (CSP) | hemolytic anemia of the fetus or newborn caused by transplacental transmission of maternally formed antibody, usually secondary to an incompatibility between the blood groups of mother and offspring. |
| Definition (MSH) | A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D004899 |
| ICD9 | 773.2, 773 |
| ICD10 | P55, P55.9 |
| SnomedCT | 123307003, 33130007, 206429000, 111468003, 276577009, 206436004, 206431009, 387705004, 157130001, 206430005, 268878003 |
| English | Erythroblastoses, Fetal, Fetal Erythroblastoses, Fetal Erythroblastosis, Hemolytic Disease of Newborn, Newborn Hemolytic Disease, Newborn Hemolytic Diseases, Hemolytic disease of fetus or newborn, due to isoimmunization, ERYTHROBLASTOSIS FETALIS, ERYTHROBLASTOSIS NEONATORUM, ERYTHROBLASTOSIS, FETALIS, HEMOLYTIC DISEASE, OF NEWBORN, Hemolytic disease of newborn, erythroblastosis fetalis, Erythroblastosis fetalis, NOS, Erythroblastosis neonatorum, NOS, Hemolytic disease of fetus or newborn due to isoimmunization, NOS, Hemolytic disease of fetus or newborn, NOS, HDN - Haemol diseas of newborn, Haemolytic dis.of newborn NOS, Haemolytic disease of fetus and newborn due to isoimmunisation, Haemolytic disease of fetus and newborn due to isoimmunisation NOS, Haemolytic disease of fetus/newborn due isoimmunisation NOS, Haemolytic disease of fetus/newborn due to isoimmunisation, Haemolytic disease of newborn, Hemolytic dis.of newborn NOS, Hemolytic disease of fetus and newborn due to isoimmunization, Hemolytic disease of fetus and newborn due to isoimmunization NOS, Hemolytic disease of fetus/newborn due isoimmunization NOS, Hemolytic disease of fetus/newborn due to isoimmunization, Erythroblastosis foetalis, NOS, Haemolytic dis.- isoimmun.NOS, Haemolytic disease due to isoimmunisation NOS, Haemolytic disease of foetus or newborn due to isoimmunization, NOS, Haemolytic disease of foetus or newborn, NOS, Hemolytic dis.- isoimmun.NOS, Hemolytic disease due to isoimmunization NOS, HEMOLYTIC DIS NEWBORN, fetal hemolysis due to isoimmunization, fetal hemolysis due to isoimmunization (diagnosis), Erythroblastosis fetalis (disorder), Hemolytic disease of fetus OR newborn (disorder), Haemolytic disease of fetus and newborn due to isoimmunisation (disorder), fetal or neonatal hemolysis due to isoimmunization, fetal or neonatal hemolysis due to isoimmunization (diagnosis), Haemolytic disease of fetus or newborn, due to isoimmunization, Haemolytic disease due to other and unspecified isoimmunization of fetus or newborn, Haemolytic disease of fetus OR newborn due to isoimmunisation, Hemolytic disease of fetus and newborn due to isoimmunization (disorder), Haemolytic disease of foetus and newborn due to isoimmunisation, NB hemolyt dis-isoim NEC, Haemolytic disease of foetus and newborn due to isoimmunisation NOS, Hemolytic disease of fetus and newborn due to isoimmunization NOS (disorder), Hemolytic disease due to isoimmunization NOS (disorder), Erythroblastosis Fetalis, Rh Disease, RhD Hemolytic Disease of the Newborn, Hemolytic Disease of the Newborn, Rhesus D Hemolytic Disease of the Newborn, Rhesus Disease, RhD HDN, Hemolytic disease of newborn, unspecified, Erythroblastosis, Fetal [Disease/Finding], disease fetus hemolytic, disease haemolytic newborn, disease haemolytic newborns, fetal erythroblastosis, hemolytic disease of the newborn, erythroblastosis foetalis, hemolytic disease newborn, hemolytic disease of newborn, Disease;haemolytic;newborn, disease hemolytic newborns, disease hemolytic newborn, disease hemolytic of newborn, diseases hemolytic newborn, icterus gravis neonatorum, erythroblastosis fetals, haemolytic disease newborn, Erythroblastosis, Fetal, Haemolytic disease due to other and unspecified isoimmunisation of foetus or newborn, Haemolytic disease of foetus or newborn, due to isoimmunisation, Erythroblastosis fetalis, Alloimmune hemolytic disease of newborn, EF - Erythroblastosis fetalis, HDN - Haemolytic disease of the newborn, HDN - Hemolytic disease of the newborn, Haemolytic disease of the newborn, Hemolytic disease of the newborn, Alloimmune haemolytic disease of newborn, Isoimmunisation of newborn, Isoimmunization of newborn, Erythroblastosis foetalis, EF - Erythroblastosis foetalis, Haemolytic disease of foetus OR newborn due to isoimmunisation, Hemolytic disease of fetus OR newborn due to isoimmunization (disorder), Hemolytic disease of fetus OR newborn due to isoimmunization, Hemolytic disease of fetus OR newborn, Haemolytic disease of foetus OR newborn, Erythroblastosis fetalis -RETIRED-, Erythroblastosis neonatorum, Haemolytic disease of fetus OR newborn, Haemolytic disease of fetus or newborn due to isoimmunisation, NOS, Haemolytic disease of fetus or newborn, NOS, Hemolytic disease due to other and unspecified isoimmunization of fetus or newborn, Hemolytic disease of fetus NOS, Hemolytic disease of newborn NOS, Erythroblastosis fetalis NOS, Erythroblastosis neonatorum NOS, Erythroblastosis Fetalis, Erythroblastosis Fetali, Fetali, Erythroblastosis, Fetalis, Erythroblastosis, Disease;hemolytic;newborn, haemolytic disease of a newborn, hemolytic disease of a newborn |
| Dutch | hemolytische aandoening van foetus of pasgeborene door iso-immunisatie, hemolytische ziekte t.g.v. andere, niet-gespecificeerde iso-immunisatie van foetus of pasgeborene, hemolytiche aandoening door andere en niet-gespecificeerde iso-immunisatie van foetus of pasgeborene, hemolytische aandoening van foetus of pasgeborene, ten gevolge van iso-immunisatie, hemolytiche aandoening van foetus of pasgeborene door iso-immunisatie, hemolytische aandoening door andere en niet-gesp iso-immunisatie van foetus of pasgeborene, erythroblastosis foetalis, Erythroblastosis foetalis, Hemolytische anemie van de pasgeborene, Icterus gravis neonatorum, Morbus haemolyticus neonatorum |
| French | Maladie hémolytique due à une autre isoimmunisation non précisée du foetus ou du nouveau-né, Maladie hémolytique due à une autre iso-immunisation non préc du foetus ou du nouveau-né, Maladie hémolytique due à une autre iso-immunisation non précisée du foetus ou du nouveau-né, Maladie hémolytique du foetus ou du nouveau-né due à une isoimmunisation, Maladie hémolytique du foetus ou du nouveau-né, due à l'isoimmunisation, Maladie hémolytique du foetus ou du nouveau-né, due à l'iso-immunisation, Maladie hémolytique des nouveau-nés, Maladie hémolytique néonatale, MHNN, Erythroblastose foetale, Érythroblastose foetale, Maladie hémolytique du nouveau-né |
| German | haemolytische Krankheit infolg sonstig u. unspezifisch Immunisierung des Fetus oder Neugeborenen, haemolytische Krankheit infolg sonstig u. unspezif Isoimmunisierung des Feten od Neugeborenen, haemolytische Krankheit des Feten oder Neugeborenen infolge Isoimmunisierung, Erythroblastose fetal, Erythroblastose, fetale, Hämolytische Erkrankung des Neugeborenen, Erythroblastosis fetalis |
| Italian | Malattia emolitica del feto o del neonato dovuta ad altra non specificata isoimmunizzazione, Malattia emolitica da altra e non specificata isoimmunizzazione fetale o neonatale, Malattia emolitica del feto o del neonato dovuta a isoimmunizzazione, Malattia emolitica fetale o neonatale da isoimmunizzazione, Malattia emolitica del neonato, Eritroblastosi fetale |
| Portuguese | Doença hemolítica por outra isoimunização e NE do feto ou recém-nascido, Doença hemolítica por isoimunização do feto ou recém-nascido, Eritroblastose fetal, Doença Hemolítica do Recém-Nascido, Eritroblastose Fetal |
| Spanish | Enfermedad hemolítica por otras isoinmunizaciones y las no especif del feto o del recién nacido, Enfermedad hemolítica del feto o del recién nacido, por isoinmunización, Enfermedad hemolítica del feto o del recién nacido por isoinmunización, Erythroblastosis foetalis, Erythroblastosis fetalis, Haemolytic disease of fetus and newborn due to isoimmunisation, Hemolytic disease of fetus and newborn due to isoimmunization, anemia hemolítica del recién nacido, no especificada, enfermedad hemolítica aloinmune del feto O recién nacido, enfermedad hemolítica aloinmune del recién nacido, enfermedad hemolítica autoinmunitaria del recién nacido, enfermedad hemolítica del feto O el recién nacido, enfermedad hemolítica del feto O recién nacido (concepto no activo), enfermedad hemolítica del feto O recién nacido (trastorno), enfermedad hemolítica del feto O recién nacido por isoinmunización (trastorno), enfermedad hemolítica del feto O recién nacido por isoinmunización, enfermedad hemolítica del feto O recién nacido, enfermedad hemolítica del feto y del recién nacido por isoinmunización, SAI (trastorno), enfermedad hemolítica del feto y del recién nacido por isoinmunización, SAI, enfermedad hemolítica del recién nacido, enfermedad hemolítica fetal o neonatal por isoinmunización, enfermedad hemolítica fetal o neonatal, enfermedad hemolítica por isoinmunización, SAI (trastorno), enfermedad hemolítica por isoinmunización, SAI, eritroblastosis fetal - RETIRADO - (concepto no activo), eritroblastosis fetal - RETIRADO -, eritroblastosis fetal, no especificada, eritroblastosis fetalis, eritroblastosis fetal, eritroblastosis neonatal, isoinmunización del recién nacido, Eritroblastosis fetal, Enfermedad Hemolítica del Recién Nacido, Eritroblastosis Fetal, Enfermedad Hemolitica del Recien Nacido |
| Japanese | 胎児あるいは新生児のその他および詳細不明の同種免疫による溶血性疾患, 胎児・新生児の同種免疫による溶血性疾患, タイジアルイハシンセイジノソノタオヨビショウサイフメイノドウシュメンエキニヨルヨウケツセイシッカン, タイジシンセイジノドウシュメンエキニヨルヨウケツセイシッカン, タイジセキガキュウショウ, 黄疸-新生児重症, 赤芽球症-胎児, 新生児溶血性疾患, 新生児重症黄疸, 胎児赤芽球症 |
| Swedish | Hemolytisk sjukdom hos nyfödda |
| Czech | erytroblastóza fetální, Hemolytické onemocnění plodu nebo novorozence při jiné a blíže neurčené izoimunizaci, Hemolytické onemocnění plodu nebo novorozence při jiné a nespecifikované izoimunizaci, Fetální erytroblastóza, Hemolytické onemocnění plodu nebo novorozence způsobené izoimunizací, Hemolytické onemocnění fetu nebo novorozence způsobené izoimunizací, Erythroblastosis fetalis |
| Finnish | Vastasyntyneen hemolyyttinen tauti |
| Russian | GEMOLITICHESKAIA BOLEZN' NOVOROZHDENNYKH, ERITROBLASTOZ PLODA, ANEMIIA GEMOLITICHESKAIA NOVOROZHDENNYKH, АНЕМИЯ ГЕМОЛИТИЧЕСКАЯ НОВОРОЖДЕННЫХ, ГЕМОЛИТИЧЕСКАЯ БОЛЕЗНЬ НОВОРОЖДЕННЫХ, ЭРИТРОБЛАСТОЗ ПЛОДА |
| Croatian | FETALNA ERITROBLASTOZA |
| Polish | Erytroblastoza płodu, Choroba hemolityczna noworodka, Choroba hemolityczna noworodków |
| Hungarian | foetus vagy újszülött haemolytikus betegsége, isoimmunisatio okozta, haemolytikus betegség a foetus vagy az újszülött egyéb és meghatározatlan isoimmunisatiója miatt, A foetus vagy újszülött haemolyticus betegség egyébe és meghatározatlan isoimmunisatiója, magzat vagy újszülött haemolyticus betegsége, isoimmunisatio okozta, Foetalis erythroblastosis, haemolytikus betegség a magzat vagy újszülött egyéb és meghatározatlan isoimmunisatiója miatt, Magzati erythroblastosis, magzat vagy újszülött haemolytikus betegsége, isoimmunisatio okozta |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |