Neonatology Book

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Hemolytic Disease of the NewbornAka: Erythroblastosis Fetalis

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  1. See Also
    1. Rh Sensitization
  2. Pathophysiology
    1. Maternal Rh Sensitization
    2. Results in fetal Hemolytic Anemia
      1. Increased Unconjugated Hyperbilirubinemia
      2. Compensating Erythropoiesis
      3. Hepatosplenomegaly
        1. Red Blood Cell production and destruction
      4. Placenta enlarged
  3. Complications
    1. Fetal hydrops
    2. Hemolytic Anemia
    3. Congenital Anemia (Mild Hemolysis)
    4. Icterus Gravis (Severe Hemolysis)
    5. Kernicterus

Erythroblastosis, Fetal (C0014761)

Definition (MSH)A condition characterized by the abnormal presence of ERYTHROBLASTS in the circulation of the FETUS or NEWBORNS. It is a disorder due to BLOOD GROUP INCOMPATIBILITY, such as the maternal alloimmunization by fetal antigen RH FACTORS leading to HEMOLYSIS of ERYTHROCYTES, hemolytic anemia (ANEMIA, HEMOLYTIC), general edema (HYDROPS FETALIS), and SEVERE JAUNDICE IN NEWBORN.
Definition (CSP)hemolytic anemia of the fetus or newborn caused by transplacental transmission of maternally formed antibody, usually secondary to an incompatibility between the blood groups of mother and offspring.
ConceptsDisease or Syndrome (T047)
ICD9773, 773.2, 773.2
MSHD004899
EnglishAlloimmune haemolytic disease of newborn, Alloimmune hemolytic disease of newborn, EF - Erythroblastosis fetalis, EF - Erythroblastosis foetalis, Erythroblastosis Fetali, erythroblastosis fetalis, Erythroblastosis fetalis -RETIRED-, Erythroblastosis foetalis, ERYTHROBLASTOSIS NEONATORUM, Fetal Erythroblastoses, Fetal Erythroblastosis, Haemolytic disease of fetus and newborn due to isoimmunisation, Haemolytic disease of fetus OR newborn, Haemolytic disease of fetus OR newborn due to isoimmunisation, Haemolytic disease of foetus OR newborn, Haemolytic disease of foetus OR newborn due to isoimmunisation, Haemolytic disease of the newborn, HDN - Haemolytic disease of the newborn, HDN - Hemolytic disease of the newborn, HEMOLYTIC DIS NEWBORN, Hemolytic disease due to other and unspecified isoimmunization of fetus or newborn, Hemolytic disease of fetus and newborn due to isoimmunization, Hemolytic disease of fetus OR newborn, Hemolytic disease of fetus OR newborn due to isoimmunization, Hemolytic Disease of Newborn, Hemolytic disease of the newborn, Isoimmunisation of newborn, Isoimmunization of newborn, NB HEMOLYT DIS-ISOIM NEC, Newborn Hemolytic Disease, Newborn Hemolytic Diseases
Spanishenfermedad hemolitica aloinmune del feto O recien nacido, enfermedad hemolitica aloinmune del recien nacido, enfermedad hemolitica autoinmunitaria del recien nacido, enfermedad hemolitica del feto O el recien nacido, enfermedad hemolitica del feto O recien nacido, enfermedad hemolitica del feto O recien nacido por isoinmunizacion, enfermedad hemolitica del recien nacido, enfermedad hemolitica fetal o neonatal, enfermedad hemolitica fetal o neonatal por isoinmunizacion, eritroblastosis fetal, eritroblastosis fetal - RETIRADO -, eritroblastosis fetalis, eritroblastosis neonatal, isoinmunizacion del recien nacido
Parent Conceptsperinatal blood group incompatibility (C0597199), Erythroblastosis, Fetal (C0014761), OTHER CONDITIONS ORIGINATING IN THE PERINATAL PERIOD (C0178309), Blood Group Incompatibility (C0005806), Fetal Diseases (C0015929), Neonatal disorder (C0021290), Anemia, Hemolytic, Acquired (C0002879), Microcytic anemia (C0085576), Ambiguous concept (C1274012), Disorder of fetus or newborn (C1533165)
SourcesCSP, CST, DXP, ICD9CM, MSH, MTHICD9, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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