II. Class

  1. Anticonvulsant

III. Indications: Adjunctive Therapy

IV. Adverse Effects: Dose related

  1. Sedation
  2. Dizziness
  3. Lethargy
  4. Tremor
  5. Nervousness

V. Adverse Effects: Other

  1. Nonconvulsive Status Epilepticus

VI. Precautions

  1. Adjust dose in hepatic disease

VII. Dose: Adults and children over age 12

  1. Initial: 4 mg PO qd for first week
  2. Increase by 4-8 mg increments per day weekly
  3. Divide daily dose to bid-qid after first week
  4. Maximum: 56 mg/day divided bid-qid

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Cost: Medications

tiagabine (on 7/13/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
TIAGABINE HCL 2 MG TABLET Generic $5.10 each
TIAGABINE HCL 4 MG TABLET Generic $4.81 each
gabitril (on 1/1/2017 at Medicaid.Gov Survey of pharmacy drug pricing)
GABITRIL 12 MG TABLET $9.63 each
GABITRIL 16 MG TABLET $12.87 each
GABITRIL 4 MG TABLET Generic $4.81 each

Ontology: tiagabine (C0068897)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C059205
SnomedCT 108403006, 372485004
LNC LP19540-1, MTHU010005
English N-(4,4-di(3-methylthien-2-yl)but-3-enyl)nipecotic acid, tiagabine, tiagabine [Chemical/Ingredient], tiaGABine, TIAGABINE, Tiagabine, Tiagabine (product), Tiagabine (substance)
Spanish tiagabina (producto), tiagabina (sustancia), tiagabina

Ontology: Gabitril (C0720560)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C059205
English Gabitril, gabitril