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PyridostigmineAka: Pyridostigmine Bromide

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  1. Indications
    1. Pretreatment before Nerve Agent Exposure (Soman)
    2. Myasthenia Gravis
  2. Pharmacokinetics: Nerve Agent Exposure
    1. Significantly enhances post-exposure antidote for Soman
    2. Does not enhance antidote for other nerve agents
    3. Raises Soman LD50 by several fold
  3. Dosing: Nerve Agent Exposure
    1. Pyridostigmine 30 mg PO every 8 hours before exposure
  4. Precautions: Nerve Agent Exposure
    1. Pyridostigmine does not protect against exposure
    2. Nerve Agent Exposures must be treated with Antidote
  5. References
    1. (1998) USAMRICD Chemical Casualties Handbook, p. 58-9

Pyridostigmine (C0034261)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
EnglishPyridostigmine, PYRIDOSTIGMINE PREPARATION
Spanishpiridostigmina
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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