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PyridostigmineAka: Pyridostigmine Bromide

Indications
1. Pretreatment before Nerve Agent Exposure (Soman)
2. Myasthenia Gravis
Pharmacokinetics: Nerve Agent Exposure
1. Significantly enhances post-exposure antidote for Soman
2. Does not enhance antidote for other nerve agents
3. Raises Soman LD50 by several fold
Dosing: Nerve Agent Exposure
1. Pyridostigmine 30 mg PO every 8 hours before exposure
Precautions: Nerve Agent Exposure
1. Pyridostigmine does not protect against exposure
2. Nerve Agent Exposures must be treated with Antidote
References
1. (1998) USAMRICD Chemical Casualties Handbook, p. 58-9

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