III. Adverse Effects: Dose related

IV. Adverse Effects: Other

  1. Hyponatremia
  2. Cardiac arrhythmia

V. Dosing

  1. Child (age 4 to 16 years old)
    1. Initial: 8-10 mg/kg/day divided twice daily
    2. May be increased by 5 mg/kg/day up to every 3 days, up to maximum dose
  2. Adult (includes elderly)
    1. Initial: 300 mg (max 600 mg) orally twice daily
    2. Increase by 300 mg/day each week

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Cost: Medications

oxcarbazepine (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing)
OXCARBAZEPINE 150 MG TABLET Generic $0.14 each
OXCARBAZEPINE 300 MG TABLET Generic $0.17 each
OXCARBAZEPINE 300 MG/5 ML SUSP Generic $0.44 per ml
OXCARBAZEPINE 600 MG TABLET Generic $0.35 each
trileptal (on 2/22/2017 at Medicaid.Gov Survey of pharmacy drug pricing)
TRILEPTAL 150 MG TABLET Generic $0.14 each
TRILEPTAL 300 MG TABLET Generic $0.17 each
TRILEPTAL 300 MG/5 ML SUSP Generic $0.44 per ml
TRILEPTAL 600 MG TABLET Generic $0.35 each

Ontology: oxcarbazepine (C0069751)

Definition (NCI) A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses.
Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C036006
SnomedCT 323042005, 116511002, 387025007
LNC LP20805-5, MTHU012038
English 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, oxcarbazepine (medication), OXCARBAZEPINE, oxcarbazepine [Chemical/Ingredient], oxcarbazepine substance, OXcarbazepine, oxcarbazepine, Oxcarbazepine (product), Oxcarbazepine (substance), Oxcarbazepine
Spanish oxcarbacepina, oxcarbazepina (producto), oxcarbazepina (sustancia), oxcarbazepina

Ontology: Trileptal (C0876196)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C036006
English trileptal, Novartis brand of oxcarbazepine, Trileptal
Japanese オクスカルバゼピン