Neurology Book

Miscellaneous

http://www.fpnotebook.com/

Cafe-Au-Lait MaculeAka: Cafe-Au-Lait Spot, Cafe Au Lait

Advertisement

  1. Pathophysiology
    1. Congenital or develops in early childhood
    2. Hyperpigmentation from increased Melanin deposition
  2. Epidemiology
    1. Often present at birth
    2. Isolated lesions are common - present in up to 30% of the population
  3. Red Flags: Criteria to consider associated conditions below
    1. Six or more lesions that meet size criteria
    2. Size criteria
      1. Prepubertal: Lesions 5 mm or larger
      2. Postpubertal: Lesions 15 mm or larger
  4. Associated Conditions
    1. Neurofibromatosis
    2. Tuberous Sclerosis
    3. Albright Syndrome
    4. Fanconi Anemia
  5. Signs
    1. "Coffee with milk" (tan to brown) colored flat Macule
    2. Usually located on trunk
    3. Size varies from <4 cm in infants to 30 cm in adults
  6. Management
    1. None needed
    2. Consider only for cosmetic reasons
  7. References

Cafe-au-Lait Spots (C0221263)

Definition (MSH)Light brown pigmented macules associated with NEUROFIBROMATOSIS and Albright's syndrome (see FIBROUS DYSPLASIA, POLYOSTOTIC).
ConceptsDisease or Syndrome (T047)
MSHD019080
EnglishCafe Au Lait Patch, CAFE AU LAIT SPOT, Cafe au Lait Spots, Cafe-au-Lait Spot, Cafe-au-lait spots
Spanishmanchas cafe con leche, manchas de color cafe con leche
Parent ConceptsSkin Manifestations (C0037285), Pigmentation Disorders (C0549567), Transdermal Patch (C0991556), Skin Pigmentation Disorder (C1704421), Duplicate concept (C1274013)
SourcesCOSTAR, DXP, MSH, NCI, NDFRT, OMIM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



Navigation Tree