Neurology Book

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LamotrigineAka: Lamictal

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  1. Indications
    1. Simple Partial Seizures
    2. Complex Partial Seizures
    3. Generalized Tonic Clonic Seizures
  2. Adverse Effects: Dose related
    1. Dizziness
    2. Incoordination
    3. Tremor
    4. Ataxia
    5. Diplopia
    6. Headache
    7. Insomnia
    8. Somnolence
    9. Blurred vision
    10. Nausea or Vomiting
  3. Adverse Effects: Other
    1. Steven's Johnson Syndrome
    2. Aplastic Anemia
    3. Thrombocytopenia
    4. Neutropenia
    5. Pancytopenia
  4. Drug Interactions
    1. Antiepileptic agents (especially Valproic Acid)
  5. Dosing: Adults
    1. Initial: 25 mg every other day for 2 weeks
    2. Next: 25 mg PO qd for 2 weeks
    3. Target dose: 50-100 mg PO bid
    4. Maximum dose: 400 mg/day

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