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Streptomycin
- Indications
- Multi-drug Tuberculosis Treatment regimen
- Background
- Only 10% of drug penetrates Tb infected cells
- Dosing
- Adult: 1 gram (15 mg/kg) IM qd
- Pediatric: 20-40 mg/kg/day
- Adverse Effects
- Cranial Nerve 8 and Vestibular toxicity
- Vertigo
- Decreased hearing acuity or deafness
- Renal damage
- Cranial Nerve 8 and Vestibular toxicity
Streptomycin (C0038425) | |
|---|---|
| Definition (MSH) | An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis. |
| Definition (CSP) | first of the aminoglycoside antibiotics to be isolated; derived from Streptomyces griseus. |
| Concepts | Carbohydrate (T118) , Antibiotic (T195) |
| MSH | D013307 |
| English | Streptomycin, STREPTOMYCIN PREPARATION |
| Spanish | estreptomicina |
| Parent Concepts | Antibiotics, Aminoglycoside (C0003233), Antitubercular Agents (C0003448), Aminoglycosides (C0002556) |
| Sources | CSP, LCH, LNC, MSH, MTHSPL, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, VANDF Derived from the NIH UMLS (Unified Medical Language System) |
