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Cough SuppressantAka: Antitussive, Benzonatate, Tessalon Perles

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  1. See Also
    1. Cough Symptomatic Treatment
    2. Cough Expectorant
  2. Indications
    1. Dry, nonproductive cough
    2. Cough interferes with sleep or activity
  3. Non-Narcotic Antitussives
    1. Benzonatate (Tessalon Perles) 100 to 200 mg PO tid
  4. Preparations: Narcotic Antitussives
    1. Dextromethorphan (Benylin DM, Delsym)
    2. Codeine
      1. Useful for night-time cough
      2. Codeine Dose: 0.3 mg/kg up to 30 mg PO tid-qid
        1. Codeine may be used alone or in combination product
      3. Guaifenesin with Codeine (Robitussin AC)
        1. Adult: 2 tsp (10 ml) q4h
        2. Age 6 to 12 years: 1 tsp (5 ml) q4h
        3. Age 2 to 6 years: 1/2 tsp (2.5 ml) q4h
    3. Hydromorphone-Guaifenesin (Hycotuss)
      1. Adult dose: 5 ml po after meals and at bedtime prn
    4. Hydrocodone (Hycodan)
      1. Adult dose: 5 mg q4-6 hours prn

Antitussive Agents (C0003449)

Definition (MSH)Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
Definition (NCI)Any substance that is capable of relieving or suppressing coughing.
ConceptsPharmacologic Substance (T121)
Englishantitussive, Antitussive agent, Antitussive Agents, Antitussive Drugs, Antitussives, Cough suppressant, Cough suppressants
Spanishagente antitusivo, antitusivos, supresores de la tos
CreditsDerived from the NIH UMLS (Unified Medical Language System)


benzonatate (C0053229)

Definition (NCI)A synthetic butylamino-benzoate derivative related to tetracaine and a peripherally acting antitussive, nonnarcotic Benzonatate reduces the cough reflex by anesthetizing and depressing mechanoreceptors in the respiratory passages, lungs, and pleura. It is recommended for cough relief in the common cold, bronchitis, pneumonia, and for chronic cough such as in asthma. (NCI04)
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
Englishbenzonatate, BENZONATATE PREPARATION
Spanishbenzonatato
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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