II. Indications

  1. Dry, nonproductive cough
  2. Cough interferes with sleep or activity

III. Preparations: Non-narcotic Antitussives

  1. Benzonatate (Tessalon Perles) 100 to 200 mg PO tid

IV. Preparations: Narcotic Antitussives

  1. Dextromethorphan (Benylin DM, Delsym)
  2. Codeine
    1. Useful for night-time cough
    2. Codeine Dose: 0.3 mg/kg up to 30 mg PO tid-qid
      1. Codeine may be used alone or in combination product
    3. Guaifenesin with Codeine (Robitussin AC)
      1. Adult: 2 tsp (10 ml) q4h
      2. Age 6 to 12 years: 1 tsp (5 ml) q4h
      3. Age 2 to 6 years: 1/2 tsp (2.5 ml) q4h
  3. Hydromorphone-Guaifenesin (Hycotuss)
    1. Adult dose: 5 ml po after meals and at bedtime prn
  4. Hydrocodone (Hycodan)
    1. Adult dose: 5 mg q4-6 hours prn

V. Preparations: Nebulized

  1. Nebulized Lidocaine 1-4% Lidocaine 3 cc
  2. Nebulized Morphine Sulfate 5-10 mg in 3 cc of Normal Saline

Images: Related links to external sites (from Google)

Cost: Medications

BENZONATATE (on 2/10/2012 at Target.com)
BENZONATATE 100 MG Capsule #30 for $4.00 ($0.13/unit)
Benzonatate (on 2/9/2012 at DrugStore.com)
Benzonatate 100mg Capsules #30 for $20.99 ($0.70/unit)
Benzonatate 200mg Capsules #30 for $33.99 ($1.13/unit)
Tessalon Perles (on 2/9/2012 at DrugStore.com)
Tessalon Perles 100mg Capsules #30 for $49.99 ($1.67/unit)

Ontology: Antitussive Agents (C0003449)

Definition (MSH) Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
Definition (NCI) Any substance that is capable of relieving or suppressing coughing.
Concepts Pharmacologic Substance (T121)
MSH D000996
SnomedCT 372791003, 59751001, 320955005, 372593002
English Agents, Antitussive, Antitussive Agents, Antitussive, Antitussive Drugs, Antitussive agents, Antitussives, Drugs, Antitussive, ANTITUSSIVE AGENTS, Antitussive, NOS, antitussive, 881 ANTITUSSIVE AGENTS, Antitussive Agent [TC], Antitussive Agent, Suppressants, Cough, Cough Suppressants, antitussive drug, antitussive drugs, coughing suppressants, cough suppressants, antitussives, cough suppressant, Cough Medicines, Cough suppressants, Cough suppressant, Antitussive agent (product), Antitussive agent (substance), Antitussive agent, Cough suppressants (product), Cough suppressants (substance)
French Médicaments antitussifs, Agents antitussifs, Anti-tussifs, Médicaments contre la toux, Antitussifs
Swedish Hostdämpande medel
Czech antitusika
Finnish Antitussiivit
Italian Antitossivi, Farmaci antitossivi, Antitussivi, Sedativi della tosse
Russian PROTIVOKASHLEVYE SREDSTVA, ПРОТИВОКАШЛЕВЫЕ СРЕДСТВА
Croatian ANTITUSICI
Spanish Agentes Antitusivos, Antitusivos, Agentes Antitusígenos, Agentes Antitusigenos, agente antitusivo (producto), agente antitusivo (sustancia), agente antitusivo, antitusivos (producto), antitusivos (sustancia), antitusivos, supresores de la tos (sustancia), supresores de la tos
Portuguese Agentes Antitussígenos, Antitussígenos
Polish Leki przeciwkaszlowe
Japanese 鎮咳剤, 咳止め, せき止め, 鎮咳薬
German Antitussiva, Hustenmittel

Ontology: benzonatate (C0053229)

Definition (NCI) A synthetic butylamino-benzoate derivative related to tetracaine and a peripherally acting antitussive, nonnarcotic Benzonatate reduces the cough reflex by anesthetizing and depressing mechanoreceptors in the respiratory passages, lungs, and pleura. It is recommended for cough relief in the common cold, bronchitis, pneumonia, and for chronic cough such as in asthma. (NCI04)
Concepts Organic Chemical (T109) , Pharmacologic Substance(T121)
MSH C029755
SnomedCT 31801005, 386030001
English benzonatate, benzonatate (medication), BENZONATATE, benzonatate [Chemical/Ingredient], Benzonatate, Benzonatate (product), Benzonatate (substance)
Spanish benzonatato (producto), benzonatato (sustancia), benzonatato