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Sweat ChlorideAka: Sweat Test

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  1. See Also
    1. Delta F508
  2. Indication
    1. Cystic Fibrosis testing
  3. Method
    1. Quantitative Pilocarpine Iontophoresis
      1. Stimulates local sweat production (parasympathetic)
      2. Collect sweat on gauze pads
      3. Analyze sodium and chloride content
    2. Minimum sweat amount required: 50 mg (200 mg better)
  4. Normal
    1. Sweat contains <60 meq/Liter Chloride and Sodium
  5. Abnormal Results
    1. CF Sweat contains > 70 meq/L Chloride and Sodium
    2. Error: >30 meq/L difference between chloride and sodium
  6. Indications to repeat the test for confirmation
    1. Positive Test
    2. Suspected false negative
  7. False positive Tests
    1. Glucose 6 phosphate dehydrogenase deficiency (G6PD)
    2. Hypothyroidism
    3. Glycogen Storage Disease
    4. Untreated Adrenal Insufficiency
    5. Malnutrition
  8. Reference
    1. Bakerman (1984) ABC's of Lab Data, ILD, Greenville, NC

Sweat test NOS (C0430179)

ConceptsLaboratory Procedure (T059)
Englishsweat analysis, Sweat screening test, Sweat test
Spanishprueba del sudor
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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