Pulmonology Book

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MesotheliomaAka: Diffuse Malignant Mesothelioma

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  1. See Also
    1. Asbestos
    2. Asbestosis
    3. Pleural Plaques
  2. Definition
    1. Asbestos-related Lung Cancer
  3. Risk Factors
    1. Asbestos Exposure (even minor exposure)
    2. Tobacco abuse
  4. Epidemiology
    1. Incidence: 2000 new cases in U.S. per year
  5. Symptoms
    1. Chest Pain
    2. Dyspnea
  6. Imaging
    1. Chest XRay
      1. Unilateral Pleural Effusion
    2. Chest CT
      1. Pleura may appear irregular
  7. Presentations
    1. Vague cardiopulmonary symptoms
    2. Superior Vena Cava Syndrome
    3. Horner's Syndrome
    4. Dysphagia
  8. Managament
    1. Palliative radiation
    2. No protocol improves survival
  9. Prognosis
    1. Uniformly fatal
    2. Median survival: 6-18 months from diagnosis
  10. References
    1. O'Reilly (2007) Am Fam Physician 75:683
    2. Robinson (2005) N Engl J Med 353:1591

Mesothelioma (C0025500)

Definition (MSH)A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Definition (CSP)malignant tumor derived from mesothelial tissues of peritoneum, pleura, and pericardium.
Definition (NCI)A benign (noncancerous) or malignant (cancerous) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma.
Definition (NCI)A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.
ConceptsNeoplastic Process (T191)
MSHD008654
EnglishMesothelioma, Mesotheliomas
Spanishmesotelioma
Parent Conceptsneoplasm/cancer type (C0872066), adenoma (C0001430), Neoplasms, Mesothelial (C0206714), Malignant mesothelioma (C0345967), Neoplasm of mesothelial tissue (C1290376), Duplicate concept (C1274013)
SourcesAOD, CSP, DXP, LCH, MEDLINEPLUS, MSH, MTH, NCI, NDFRT, PDQ, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Diffuse malignant mesothelioma (C0392400)

ConceptsNeoplastic Process (T191)
EnglishDiffuse malignant mesothelioma, DMM, Malignant Diffuse Mesothelioma
Parent ConceptsMalignant mesothelioma (C0345967)
SourcesDXP, MTH, NCI
Derived from the NIH UMLS (Unified Medical Language System)



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