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MesotheliomaAka: Diffuse Malignant Mesothelioma

See Also
Definition
1. Asbestos-related Lung Cancer
Risk Factors
1. Asbestos Exposure (even minor exposure)
2. Tobacco abuse
Epidemiology
1. Incidence: 2000 new cases in U.S. per year
Symptoms
1. Chest Pain
2. Dyspnea
Imaging
1. Chest XRay
  1. Unilateral Pleural Effusion
2. Chest CT
  1. Pleura may appear irregular
Presentations
1. Vague cardiopulmonary symptoms
2. Superior Vena Cava Syndrome
3. Horner's Syndrome
4. Dysphagia
Managament
1. Palliative radiation
2. No protocol improves survival
Prognosis
1. Uniformly fatal
2. Median survival: 6-18 months from diagnosis
References
1. O'Reilly (2007) Am Fam Physician 75:683
2. Robinson (2005) N Engl J Med 353:1591

Mesothelioma (C0025500)
Definition (MSH)	A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
Definition (CSP)	malignant tumor derived from mesothelial tissues of peritoneum, pleura, and pericardium.
Definition (NCI)	A benign (noncancerous) or malignant (cancerous) tumor affecting the lining of the chest or abdomen. Exposure to asbestos particles in the air increases the risk of developing malignant mesothelioma.
Definition (NCI)	A usually malignant and aggressive neoplasm of the mesothelium which is often associated with exposure to asbestos.
Concepts	Neoplastic Process (T191)
English	Mesothelioma, Mesotheliomas
Spanish	mesotelioma
Credits	Derived from the NIH UMLS (Unified Medical Language System)

Diffuse malignant mesothelioma (C0392400)
Concepts	Neoplastic Process (T191)
English	Diffuse malignant mesothelioma, DMM, Malignant Diffuse Mesothelioma
Credits	Derived from the NIH UMLS (Unified Medical Language System)