Infectious Disease Book

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ChancroidAka: Soft Chancre

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  1. Epidemiology
    1. Uncommon in United States except urban centers
      1. Outbreak in L.A. 1987
    2. Reportable disease
    3. Coinfection with other STD is common
      1. Herpes Simplex Virus 2 (Genital Herpes)
      2. Syphilis
  2. Pathophysiology
    1. Venereal infection with Haemophilus ducreyi
    2. Incubation: under 1 week
  3. Symptoms
    1. Malaise
    2. Headache
    3. Anorexia
    4. Extremely painful Genital Ulcers
  4. Signs
    1. Fever
    2. Small Red Papules begin on genitalia or adjacent skin
    3. Lesions suppurate into soft painful Genital Ulcers
      1. Deep, Undermined edges
      2. Irregular borders
      3. Purulent base
      4. Multiple lesions in two thirds of patients
    4. Regional tender inguinal lymphadenitis (bubo)
      1. Occurs in one third of patients
  5. Labs
    1. Haemophilus ducreyi bacilli in smear or culture
  6. Management
    1. Azithromycin 1 gram PO x1 dose
    2. Ceftriaxone 250 mg IM x1 dose
    3. Ciprofloxacin 500 mg PO bid for 3 days
    4. Erythromycin 500 mg PO qid for 7 days

Chancroids (C0007947)

Definition (MSH)Acute, localized autoinoculable infectious disease usually acquired through sexual contact. Caused by HAEMOPHILUS DUCREYI, it occurs endemically almost worldwide, especially in tropical and subtropical countries and more commonly in seaports and urban areas than in rural areas.
ConceptsDisease or Syndrome (T047)
ICD9099.0
EnglishBubo chancroidal, Bubo due to Haemophilus ducreyi, Bubo due to Hemophilus ducreyi, Chancroid, Chancroidal bubo, Chancroids, Ducrey's chancre, Ducrey's disease, Ducrey's simple soft chancre, Haemophilus ducreyi, Simple chancre, Soft chancre, Ulcus molle
Spanishbubón chancroide, bubón por Haemophilus ducreyi, bubón virulento, bubon chancroide, bubon por Haemophilus ducreyi, bubon virulento, chancro, chancro blando, chancro de Ducrey, chancro simple, chancroide, enfermedad de Ducrey
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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