Infectious Disease Book

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Griseofulvin

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  1. General
    1. Take with Fatty Meal for better absorption
  2. Indications
    1. Tinea Capitis
  3. Duration
    1. Tinea Capitis
      1. Eight to sixteen weeks of therapy or
      2. Two weeks after cultures are negative
  4. Efficacy
    1. Very effective for Tinea Capitis over 2-4 months
    2. Not as effective for Tinea Unguium
  5. Dosing
    1. Adults
      1. Griseofulvin 1 gram per day
      2. Ultramicrosize 350-750 mg (better absorption)
    2. Children
      1. Griseofulvin 10-12 mg/kg/day
  6. Precautions: Follow Liver Function Tests if
    1. Baseline abnormal
    2. Prolonged therapy
  7. Directions
    1. Take with food (especially a fatty meal)

Griseofulvin (C0018242)

Definition (MSH)An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
ConceptsOrganic Chemical (T109) , Antibiotic (T195)
EnglishGriseofulvin, GRISEOFULVIN PREPARATION
Spanishgriseofulvina
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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