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Lyme Disease TestAka: Lyme Culture, Lyme PCR

See Also
1. Lyme Disease
2. Lyme Titer
Tests: Lyme Titer (first Line)
1. Tier 1: Lyme ELISA
2. Tier 2: Lyme Western Blot
Tests: Others (recommended only in research)
1. Cerebrospinal fluid (CSF) for Lyme Disease
  1. Indicated for neurologic symptoms
2. Skin Biopsy of Erythema Migrans for Quantitative PCR
  1. Most sensitive test in early Erythema Migrans
  2. May be indicated in atypical rash presentations
  3. Sensitivity: 81%
  4. Nowakowski (2001) Clin Infect Dis 33:2023
3. Skin Culture of Erythema Migrans
  1. Sensitivity: 60-80% for organisms
  2. Sample types
    1. Saline-lavage needle aspirate
    2. Punch Biopsy (2 mm) of leading edge

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 5/10/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.