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Gonorrhea AntigenAka: Gonococcal Antigen, Gonozyme

Indications
1. Testing for Neisseria Gonorrhea: Urethra, Cervix
2. Not indicated for GC testing of throat or anus
Mechanism
1. Enzyme Immunoassay
Technique
1. Cervical Specimen
  1. Avoid lubricating gel (may kill Gonococcus)
  2. Wipe clean cervix with swab
  3. Compress cervix between speculum blades
    1. Produces endocervical exudate
  4. Rotate swab in endocervical canal for 10-30 seconds
  5. Avoid touching side walls of vagina with swab
2. Urethra Specimen (Males)
  1. Gently scrape anterior meatus with swab
Efficacy
1. Sensitivity: 98% Men, 88% Women
2. Specificity: 100% Men, 98% Women
References
1. Bakerman (1984) ABCs of Interpretive Lab Data

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 5/10/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.