Td Vaccine

Aka: Td Vaccine, Tetanus Diphtheria Vaccine, Tetanus Toxoid, Tetanus Vaccine, Tenivac, Tdvax

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II. Indications

  1. See Tetanus Prophylaxis
  2. Largely replaced in U.S. by Tetanus Vaccines that contain diptheria and Pertussis (Tdap Vaccine)
  3. Use DTaP Vaccine instead for children under age 7 years
  4. Use Tdap Vaccine instead for teens over age 11 and adults under age 65 years old

III. Dose

  1. Adult 0.5 ml IM
  2. Interval
    1. Low risk patients: every 8-10 years
    2. Following contaminated wound if >5 years from prior Vaccine
    3. Risk of repeat exposure: every 5 years
  3. Warming Vaccine in hands does not reduce pain
    1. Maiden (2003) Med J Aust 178:433-6 [PubMed]

IV. Safety

  1. Safe in HIV
    1. See Immunization in HIV
  2. Safe in Pregnancy (wait until after first trimester)
    1. See Immunzation in Pregnancy
  3. Anaphylaxis rare
  4. No death has been associated with Vaccine since 1978
  5. References
    1. (1996) MMWR Morb Mortal Wkly Rep 45(No. RR-12):1-35 [PubMed]

V. Efficacy

  1. Immunity from tetanus Vaccination appears to be far more long lasting than 10 years
    1. Hammarlund (2016) Clin Infect Dis 62(9):1111-8 +PMID: 27060790 [PubMed]

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