Hematology and Oncology Book

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Sarcoma

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  1. Definition
    1. Cancer arrising in mesenchymal (connective) tissue
    2. Derived from greek word "sar" meaning fleshy
  2. Types
    1. Soft-tissue sarcomas
      1. Kaposi's Sarcoma
      2. Hepatic angiosarcoma
      3. Rhabdomyosarcoma
        1. Most common soft tissue sarcoma in children
      4. Leiomyosarcoma
        1. Involves uterus in adults
        2. Involves retroperitoneum in children
      5. Liposarcoma
        1. Rare adipose tumor (usually invades locally only)
        2. Involves deep thigh or retroperitoneum
      6. Fibrosarcoma
        1. Most common soft tissue sarcoma in age <1 year
        2. Involves deep thigh or retroperitoneum
    2. Vascular sarcoma
      1. Angiosarcoma
      2. Hemangioendothelioma
      3. Hemangiopericytoma
    3. Bone tumors
      1. Ewing's Sarcoma
      2. Osteogenic Sarcoma

sarcoma (C1261473)

Definition (MSH)A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Definition (CSP)any of a group of tumors usually arising from connective tissue, although the term now includes some of epithelial origin; most are malignant.
Definition (NCI)A usually aggressive malignant mesenchymal cell tumor most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the tumor. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.
Definition (NCI)A cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.
Definition (NCI)Abnormal growth of the cells comprising the soft tissue, excluding metastatic tumors that arise in the soft tissue. This concept specifically refers to tumors with malignant characteristics.
ConceptsNeoplastic Process (T191)
EnglishConnective Tissue Sarcoma, Malignant mesenchymal tumor, Malignant mesenchymal tumour, Malignant neoplasm of soft tissue, Malignant neoplasm of soft tissues, Malignant Neoplasm of the Soft Tissue, Malignant Soft Tissue Neoplasm, Malignant Soft Tissue Tumor, Malignant tumor of soft tissue, Malignant Tumor of the Soft Tissue, Malignant tumour of soft tissue, sarcoma, Sarcoma of Soft Tissue, Sarcoma of Soft Tissue and Bone, Sarcoma of the Soft Tissue, Sarcoma of the Soft Tissue and Bone, Sarcomas, Soft Tissue Sarcoma, Soft Tissue Sarcomas
Spanishneoplasia maligna de partes blandas, neoplasia maligno de partes blandas, sarcoma, sarcoma de partes blandas, tumor maligno de partes blandas, tumor mesenquimatico maligno, tumor mesenquimatoso maligno
Parent ConceptsEpithelioma (C1368683), neoplasm/cancer type (C0872066), Malignant Neoplasms (C0006826), Disorders, General, Functional and NEC (C0549512), Connective and Soft Tissue Neoplasm (C0206765), Soft Tissue Neoplasms (C0037579), sarcoma (C1261473), Duplicate concept (C1274013), Sarcoma - category (C1299262), Primary malignant neoplasm (C1306459), Ambiguous concept (C1274012)
SourcesAOD, COSTAR, CSP, CST, LCH, MEDLINEPLUS, MSH, MTH, NCI, NDFRT, OMIM, PDQ, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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