Hematology and Oncology Book

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TiclopidineAka: Ticlid

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  1. Mechanism
    1. Blocks Platelet ADP
    2. Inhibits platelet aggregation
  2. Indications
    1. Consider other agents (e.g. Plavix) due to toxicity
    2. Cerebrovascular Accident Prevention
  3. Adverse Effects
    1. Thrombotic Thrombocytopenic Purpura (TTP)
    2. Neutropenia
  4. Dosing (Avoid if possible)
    1. Ticlid 250 mg PO bid with food

Ticlopidine (C0040207)

Definition (MSH)Ticlopidine is an effective inhibitor of platelet aggregation. The drug has been found to significantly reduce infarction size in acute myocardial infarcts and is an effective antithrombotic agent in arteriovenous fistulas, aorto-coronary bypass grafts, ischemic heart disease, venous thrombosis, and arteriosclerosis.
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD013988
EnglishTiclopidine, TICLOPIDINE PREPARATION
Spanishticlopidina
Parent ConceptsThiophenes (C0039931), Antiplatelet Agents (C0085826), Platelet Aggregation Inhibitors (C0032177), Drug allergen (C1320237)
SourcesLCH, LNC, MSH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Ticlid (C0733418)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD013988
EnglishTiclid
SourcesMSH, NCI, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)



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