Hematology and Oncology Book

http://www.fpnotebook.com/

ChemotherapyAka: Chemotherapy Extravasation

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  1. General
    1. Exercise encouraged following high dose chemotherapy
      1. Safe
      2. Prevents deconditioning
      3. Decreases toxic side effects of chemotherapy
    2. Reference
      1. Dimeo (1997) Blood 90:3390
  2. Agents
    1. Alkylating Agent
    2. Antimetabolite Chemotherapy
    3. Hormonally Active Chemotherapy
    4. Plant Alkaloid Chemotherapy
    5. Antibiotic Chemotherapy
    6. Miscellaneous Medication
      1. Amsacrine
      2. Asparaginase
      3. Hydoxyurea
      4. Mitoxantrone
      5. Mitotane (Lysodren)
      6. Quinacrine
  3. Management: Extravasation of agents from IV
    1. Findings: Onset with hours of chemotherapy
      1. Local erythema and swelling
      2. Necrosis
    2. Management
      1. Immediately stop any infusion
      2. Apply ice to area
      3. Do not compress area
      4. Use antidotes if available
      5. Urgent consultations with Oncology and Surgery
        1. Debridement may be needed
    3. Complications
      1. Scarring
      2. Contractures
    4. References
      1. Higdon (2006) Am Fam Physician 74:1873

Pharmacotherapy (C0013216)

Definition (CSP)application of the beneficial effects of drugs to control or cure diseases or abnormal states in living organisms or tissues.
Definition (HL7V3.0)<p>The introduction of a drug into a subject with the intention of altering its biologic state with the intent of improving its health status.</p>
Definition (NCI)Treatment of disease through the use of drugs.
ConceptsTherapeutic or Preventive Procedure (T061)
MSHD004358
EnglishCHEMOTHER, Chemotherapies, Chemotherapy, CT - Chemotherapy, DRUG THER, Drug Therapies, Drug Therapy, DT - Drug therapy, medication therapy, Pharmacological Treatment, Pharmacological Treatments, PHARMACOTHER, pharmacotherapeutics, Pharmacotherapies, Pharmacotherapy, THER DRUG, Treatment With Medication
Spanishfarmacoterapia, quimioterapia
Parent Conceptsmedical treatment method (C0679624), Therapeutic procedure (C0087111), ActSubstanceAdministrationCode (C1699064), The science and art of healing (C0039796), Medication Management (C0150270), Pharmacotherapy (C0013216), Ambiguous concept (C1274012), Duplicate concept (C1274013)
SourcesAOD, CSP, HL7V3.0, LCH, LNC, MEDLINEPLUS, MSH, MTH, NCI, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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