Hematology and Oncology Book

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Antiplatelet Therapy for Vascular Disease

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  1. Guidelines
    1. Aspirin or Clopidogrel
      1. Initial Transient Ischemic Attack (TIA)
      2. Initial Ischemic Cerebrovascular Accident (CVA)
      3. Chronic stable Angina
      4. Peripheral Arterial Disease
    2. Aspirin and Clopidogrel
      1. ST segment elevation Acute Coronary Syndrome
      2. Recurrent Acute Coronary Syndrome
    3. Aspirin and Extended release Dipyridamole
      1. Recurrent Transient Ischemic Attack (TIA)
      2. Recurrent Ischemic Cerebrovascular Accident (CVA)
    4. References
      1. Tran (2004) JAMA 292:1867
  2. Protocol: Post-Myocardial Infarction
    1. Aspirin 162 mg orally daily indefinately
    2. Clopidogrel (Plavix) added to Aspirin routinely following ST Elevation MI
      1. Dose: 75 mg orally daily (consider initial 300 mg loading dose if age <75 years)
      2. Duration following ST Elevation MI
        1. See Clopidogrel
    3. References
      1. Antman (2008) Circulation 117(2):296

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