II. Epidemiology

  1. Present in 2% of patients over age 50
  2. Ultimately responsible for 20% of Multiple Myeloma cases after progression

III. Evaluation: Factors suggesting higher risk of Multiple Myeloma progression

  1. Criteria
    1. Elevated M Protein Level >1.5 g/dl
    2. Non-IgG MGUS
    3. Abnormal free light chain ratio
  2. Interpretation
    1. Risk of Multiple Myeloma is 58% in 20 years if all 3 factors present

IV. Monitoring

  1. Repeat labs every 6-12 months to monitor for progression to Multiple Myeloma

V. Course

  1. Progresses to Multiple Myeloma in 1% of cases per year

Images: Related links to external sites (from Bing)

Related Studies (from Trip Database) Open in New Window