Hematology and Oncology Book

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Lymphoma

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  1. Pathophysiology
    1. Cell neoplasia residing in lymphoid tissue
    2. Reticuloendothelial organ infiltration
  2. Types
    1. Hodgkin's Lymphoma
      1. Localized disease with contiguous nodal spread
      2. Mediastinal involvement
      3. Curability >75%
      4. Systemic Symptoms (Fever, Night Sweats, weight loss)
    2. Non-Hodgkin's Lymphoma
      1. Non-contiguous nodal spread
      2. Extranodal involvement
      3. Abdominal and Bone Marrow involvement
      4. Curability <25%
  3. Risk Factors
    1. Inherited Immunodeficiency Disease
      1. Klinefelter's Syndrome
      2. Chediak-Higashi Syndrome
      3. Ataxia telangiectasia syndrome
      4. Wiskott-Aldrich Syndrome
      5. Common variable Immunodeficiency disease
    2. Acquired Immunodeficiency
      1. Iatrogenic immunosuppression
      2. Acquired Immunodeficiency Syndrome
      3. Acquired hypogammaglobulinemia
    3. Autoimmune Disease
      1. Sjogren's Syndrome
      2. Nontropical sprue
      3. Rheumatoid Arthritis
      4. Systemic Lupus Erythematosus
    4. Chemical or drug exposure
      1. Phenytoin (Dilantin)
      2. Radiation Therapy
      3. Chemotherapy
    5. Viral Association
      1. Epstein-Barr Virus
      2. Human T-Cell Leukemia Virus

Lymphoma (C0024299)

Definition (MSH)A general term for various neoplastic diseases of the lymphoid tissue.
Definition (CSP)malignant (clonal) proliferation of B- or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites; general term for various neoplastic diseases of the lymphoid tissue.
Definition (NCI)(lim-FO-ma) Cancer that arises in cells of the lymphatic system.
Definition (NCI)A malignant (clonal) proliferation of B- or T- lymphocytes which involves the lymph nodes, bone marrow and/or extranodal sites. This category includes Non-Hodgkin lymphomas and Hodgkin lymphomas.
ConceptsNeoplastic Process (T191)
ICD9200.8, 202.8
EnglishGerminoblastic Sarcoma, Germinoblastic Sarcomas, Germinoblastoma, Germinoblastomas, Lymphoma, LYMPHOMA MALIGNANT, Lymphomas, Malignant lymphoma, Malignant Lymphomas, Reticulolymphosarcoma, Reticulolymphosarcomas
Spanishlinfoma, linfoma maligno, reticulolinfosarcoma
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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