I. Epidemiology

  1. Incidence: 13 per 100,000 people per year
  2. Higher Incidence in men
  3. Age distribution
    1. All Ages
      1. Acute Myelogenous Leukemia (AML)
    2. Young
      1. Acute Lymphocytic Leukemia (ALL)
    3. Elderly
      1. Chronic Lymphocytic Leukemia
      2. Hairy Cell Leukemia

II. Types

III. Pathophysiology

  1. Malignant neoplasm of hematopoietic origin
  2. Origins
    1. Myeloid (Bone Marrow)
    2. Lymphoid
  3. Acute (Proliferating cell fails to mature past blast)
    1. AML: Immature clonal myeloid Cells (Myeloblast)
    2. ALL: Immature clonal lymphoid Cells (Lymphoblast)

IV. Predisposing Factors

  1. Idiopathic
  2. Human T-Cell Leukemia Virus (HTLV-1)
  3. Congenital syndrome
    1. Down's Syndrome
    2. Bloom's Syndrome
    3. Klinefelter's Syndrome
    4. Fanconi's Syndrome
    5. Wiskott-Aldrich Syndrome
  4. Environmental Factors
    1. Ionizing Radiation exposure (risk of CML, AML, ALL)
    2. Chemical exposure (risk of AML)
      1. Aromatic hydrocarbons (e.g. Benzene)
      2. Alkylating Agents
      3. Chemotherapeutic drugs

Images: Related links to external sites (from Google)

Ontology: Other specified leukemia (disorder) (C0029812)

Concepts Neoplastic Process (T191)
ICD9 207, 207.8
ICD10 C94.7 , C94.80, C94.8
SnomedCT 190161003, 188751002, 188761009
English Other specified leukemia, Other specified leukaemia, Other specified leukaemia NOS, Other specified leukaemias, Other specified leukemia NOS, Other specified leukemias, [X]Other specified leukaemias, [X]Other specified leukemias, Other specified leukemia (disorder), [X]Other specified leukemias (disorder), Other specified leukemia NOS (disorder), Other specified leukemias NOS
Dutch andere gespecificeerde leukemieën, andere gespecificeerde leukemie, Overige gespecificeerde vormen van leukemie
French Autre leucémies précisées, Autre leucémie précisée
German sonstige spezifische Leukaemie, sonstige spezifische Leukaemien, Sonstige naeher bezeichnete Leukaemien
Italian Altre leucemie specifiche, Altra leucemia specificata
Portuguese Outra leucemia especificada, Outras leucemias especificadas
Spanish Otras leucemias especificadas, Otra leucemia especificada, [X]otras leucemias especificadas (trastorno), [X]otras leucemias especificadas, otra leucemia especificada (trastorno), otra leucemia especificada, SAI (trastorno), otra leucemia especificada, SAI, otra leucemia especificada
Japanese その他の明示された白血病, ソノタノメイジサレタハッケツビョウ
Czech Jiná blíže určená leukemie, Jiné blíže určená leukemie
Korean 기타 명시된 백혈병
Hungarian Egyéb meghatározott leukemia, Egyéb meghatározott leukaemia, Egyéb meghatározott leukemiák