I. See Also

II. Characteristics

  1. Function: Phagocytizes dead or damaged cells
    1. Monocytes move into tissue and become Macrophages
    2. Transformation to Macrophages controlled by cytokines
    3. Macrophages directly perform the phagocytosis
  2. Monocyte Morphology on Blood Smear
    1. Mononuclear Leukocyte (same class as Lymphocyte)
    2. Slightly larger than a Lymphocyte
    3. Kidney shaped nucleus

III. Normal

  1. Range: 2-8% of White Blood Cells

IV. Increased

V. Decreased

  1. Aplastic Anemia
  2. Lymphocytic Anemia
  3. Glucocorticoids

Images: Related links to external sites (from Google)

Ontology: macrophage (C0024432)

Definition (CHV) a kind of white blood cell
Definition (CHV) a kind of white blood cell
Definition (CSP) mononuclear phagocytes found in tissue.
Definition (MSH) The relatively long-lived phagocytic cell of mammalian tissues that are derived from blood MONOCYTES. Main types are PERITONEAL MACROPHAGES; ALVEOLAR MACROPHAGES; HISTIOCYTES; KUPFFER CELLS of the liver; and OSTEOCLASTS. They may further differentiate within chronic inflammatory lesions to EPITHELIOID CELLS or may fuse to form FOREIGN BODY GIANT CELLS or LANGHANS GIANT CELLS. (from The Dictionary of Cell Biology, Lackie and Dow, 3rd ed.)
Definition (NCI) A type of white blood cell that surrounds and kills microorganisms, removes dead cells, and stimulates the action of other immune system cells.
Concepts Cell (T025)
MSH D008264
SnomedCT 58986001
HL7 MAC
English Macrophages, Monocytes / Macrophages / APC, macrophages, Macrophage, Macrophage (cell), macrophage, Bone Marrow Derived Macrophages, Bone Marrow-Derived Macrophages, Bone Marrow-Derived Macrophage, Macrophage, Bone Marrow-Derived, Macrophage, Monocyte-Derived, Macrophages, Bone Marrow-Derived, Macrophages, Monocyte Derived, Macrophages, Monocyte-Derived, Monocyte Derived Macrophages, Monocyte-Derived Macrophages, Monocyte-Derived Macrophage
French MDM (Macrophage Dérivé de Monocyte), Macrophages, Macrophages dérivés de monocytes, Macrophage, Macrophages dérivés de la moelle osseuse
Swedish Makrofager
Czech makrofágy
Finnish Makrofagit
German Knochenmark-generierte Makrophagen, Makrophagen, Monozyten-generierte, Makrophage, Monozyten-generierte Makrophagen, Makrophagen
Russian MAKROFAGI, GISTIOTSIT-MAKROFAG, GISTOFAGOTSIT, ГИСТИОЦИТ-МАКРОФАГ, ГИСТОФАГОЦИТ, МАКРОФАГИ
Italian Macrofago, Macrofagi derivati dai monociti, Macrofagi derivati dal midollo osseo, Macrofagi
Croatian MAKROFAGI
Latvian Makrofāgi
Polish Makrofagi
Japanese マクロファージ, 大食球, 大食細胞(ダイショクサイボウ), 大食細胞
Spanish macrófago (célula), macrófago, Macrófagos, Macrofagos, Macrofagos Derivados de Monocitos, Macrofagos Derivados de la Medula Osea, Macrófagos Derivados de Monocitos, Macrófagos Derivados de la Médula Ósea
Dutch Macrofaag, Macrofagen
Portuguese Macrófagos, Macrófagos Derivados da Medula Óssea, Macrófagos Derivados de Monócitos

Ontology: Monocytes (C0026473)

Definition (NCI) A type of immune cell that is made in the bone marrow and travels through the blood to tissues in the body where it becomes a macrophage. Macrophages surround and kill microorganisms, ingest foreign material, remove dead cells, and boost immune responses. A monocyte is a type of white blood cell and a type of phagocyte.
Definition (MSH) Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
Definition (NCI) Large, phagocytic mononuclear leukocytes produced in the vertebrate bone marrow and released into the blood; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
Definition (CSP) large, phagocytic mononuclear leukocytes produced in the vertebrate bone marrow and released into the blood and tissues where they develop into macrophages; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles.
Concepts Cell (T025)
MSH D009000
SnomedCT 55918008
English Monocyte, NOS, monocytes, Monocytic, monocyte, Blood monocyte, Marrow monocyte, Blood monocytes, Monocytes, blood monocytes, monocytic, Monocyte, Monocyte (cell)
Dutch bloed monocyten, monocyten, Monocyt, Monocyten
French Monocytes sanguins, Monocyte, Monocytes
German Monozyten im Blut, Monozyten
Italian Monociti ematici, Monocita, Monociti
Portuguese Monócitos no sangue, Monócitos
Spanish Monocitos en sangre, monocito (célula), monocito, Monocitos
Japanese 血中単球, ケッチュウタンキュウ, タンキュウ, 単球
Swedish Monocyter
Czech monocyty, Monocyty v krvi, Monocyty
Finnish Monosyytit
Russian MONOTSITY, МОНОЦИТЫ
Croatian MONOCITI
Latvian Monocīti
Polish Monocyty
Hungarian Monocita vérszint, Monociták