I. Background

  1. Not as useful as other indices for Anemia Evaluation
  2. More useful indices
    1. Hemoglobin or Hematocrit
    2. Mean Corpuscular Volume (MCV)
    3. Red Cell Distribution Width (RDW)

II. Calculations

  1. Mean Corpuscular Hemoglobin (MCH)
    1. MCH = (10 x Hemoglobin) / (Red Blood Cell Count)
  2. Mean Corpuscular Hemoglobin Concentration (MCHC)
    1. MCHC = (Hemoglobin x 100) / (Hematocrit)

III. Interpretations

  1. Mean Corpuscular Hemoglobin (MCH)
    1. Normal: >30 pg/cell
    2. Abnormal: <30 pg/cell
      1. Suggests abnormal Hemoglobin synthesis
  2. Mean Corpuscular Hemoglobin Concentration (MCHC)
    1. Normal: 28 - 33%
    2. Low (< 28%): Iron Deficiency Anemia
    3. High (> 33%): Spherocytosis or unstable Hemoglobin

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Ontology: Erythrocyte Mean Corpuscular Hemoglobin Test (C0369183)

Definition (NCI_CDISC) A quantitative measurement of the mean amount of hemoglobin per erythrocyte in a biological specimen.
Definition (NCI) The mean cell hemoglobin (MCH) , which is the average amount of hemoglobin in the average red cell. The MCH is a calculated value derived from the measurement of hemoglobin and the red cell count.
Concepts Laboratory Procedure (T059)
SnomedCT 165443007, 142854008, 142847002, 165436001, 54706004
Italian Emoglobina cellulare media, Emoglobina corpuscolare media, ECM
Dutch mean corpuscular hemoglobin, MCH, mean cell hemoglobin
French Hémoglobine cellulaire moyenne, Hémoglobine corpusculaire moyenne, HCM, Teneur moyenne des hématies en hémoglobine, Teneur corpusculaire moyenne en hémoglobine
German MCH, mittlerer Haemoglobingehalt der Erythrozyten, mittlerer Haemoglobingehalt des Erythrozyten, Haemoglobingehalt der Erythrozyten
Portuguese HGM, Hemoglobina globular média
Spanish HCM, determinación de HCM, SAI, determinación de hemoglobina corpuscular media, SAI, determinación de hemoglobina corpuscular media, SAI (procedimiento), MCH - NOS, determinación de HCM, determinación de hemoglobina corpuscular media (procedimiento), determinación de hemoglobina corpuscular media, Hemoglobina corpuscular media
Japanese 平均赤血球ヘモグロビン, MCH, ヘイキンセッケッキュウヘモグロビン, MCH
English Erythrocyte Mean Corpuscular Hemoglobin, Erythrocyte Mean Corpuscular Hemoglobin Test, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin (MCH) (lab test), mean corpuscular hemoglobin, Mean corpuscular haemoglobin (MCH) - NOS (procedure), Mean corpuscular haemoglobin, Mean corpuscular hemoglobin, MCH, mean corpuscular hemoglobin (MCH) test, mean cell haemoglobin, mean cell hemoglobin, MCH - NOS (procedure), Mean corpuscular hemoglobin (MCH) - NOS, MCH - NOS, Mean cell haemoglobin (& level), Mean corpuscular haemoglobin (MCH) - NOS, Mean cell haemoglobin (& level) (procedure), Mean cell hemoglobin (& level), Mean corpuscular hemoglobin NOS, Mean corpuscular haemoglobin NOS, Mean corpuscular hemoglobin NOS (procedure), Ery. Mean Corpuscular Hemoglobin, Mean corpuscular hemoglobin determination, MCH determination, MCH - Mean cell haemoglobin, MCH - Mean cell hemoglobin, Mean cell haemoglobin, Mean cell hemoglobin, Mean corpuscular haemoglobin determination, MCH - Mean corpuscular haemoglobin, MCH - Mean corpuscular hemoglobin, Mean corpuscular hemoglobin determination (procedure)
Czech Střední hmotnost hemoglobinu v erytrocytu
Hungarian Vörösvértest átlagos haemoglobin, Vörösvértestek átlagos haemoglobin tartalma, Vörösvértest átlagos hemoglobin tartalom, MCH, Vörösvértestek átlagos hemoglobin tartalma

Ontology: Mean corpuscular hemoglobin concentration determination (C0474535)

Definition (NCI_CDISC) A quantitative measurement of the mean amount of hemoglobin per erythrocytes in a specified volume of a biological specimen.
Definition (NCI) The mean cell hemoglobin concentration (MCHC), which is the average concentration of hemoglobin in a given volume of blood. The MCHC is a calculated value derived from the measurement of hemoglobin and the hematocrit.
Definition (MSH) MCHC equals HEMOGLOBIN divided by HEMATOCRIT.
Concepts Laboratory Procedure (T059)
MSH D004909
SnomedCT 165450006, 103206002, 142861007, 37254006
LNC LP17695-5, MTHU013638
English Mean cell haemoglobin concentration, Mean cell hemoglobin concentration, MCHC - NOS (procedure), mean corpuscular hemoglobin concentration (MCHC) (lab test), mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin concentration (MCHC), MCHC, MCHC - NOS (finding), Mean corpuscular hemoglobin concentration (MCHC) - NOS, Mean corpuscular hemoglobin concentration (MCHC) - NOS (procedure), MCHC - NOS, Erythrocyte mean corpuscular hemoglobin concentration (observable entity), Mean corpuscular haemoglobin concentration (MCHC) - NOS, Ery. Mean Corpuscular HGB Concentration, Erythrocyte Mean Corpuscular Hemoglobin Concentration, Mean Cell Hemoglobin Concentration, MCHC determination, MCHC - Mean cell haemoglobin concentration, MCHC - Mean cell hemoglobin concentration, Mean corpuscular haemoglobin concentration determination, Mean corpuscular hemoglobin concentration determination (procedure), Mean corpuscular hemoglobin concentration determination, Mean Corpuscular Hemoglobulin Concentration, Erythrocyte mean corpuscular haemoglobin concentration, Erythrocyte mean corpuscular hemoglobin concentration
Italian Concentrazione emoglobinica cellulare media, Concentrazione ECM, Concentrazione emoglobinica corpuscolare media
Dutch MCHC, mean cell hemoglobin concentration
French CHCM, Concentration cellulaire moyenne en hémoglobine, Concentration corpusculaire moyenne en hémoglobine, CCMH, Concentration corpusculaire moyenne en Hb
German mittlere Haemoglobinkonzentration der Erythrozyten, MCHC, Mittlerer Erythrozytenhämoglobingehalt, mittlere Ery-Haemoglobinkonzentration, Erythrozytenhämoglobingehalt, mittlerer, Hämoglobingehalt, mittlerer Erythrozyten-
Portuguese CHGM, Concentração de hemoglobina globular média
Japanese MCHC, 平均赤血球ヘモグロビン濃度, ヘイキンセッケッキュウヘモグロビンノウド, MCHC
Czech Střední koncentrace hemoglobinu v erytrocytu
Hungarian Vörösvértest átlagos hemoglobin koncentráció, MCHC, Vörösvértest átlagos haemoglobin koncentráció
Spanish concentración eritrocítica de hemoglobina corpuscular media, concentración de hemoglobina eritrocítica corpuscular media (entidad observable), determinación de CHCM, SAI, determinación de concentración hemoglobínica corpuscular media, SAI (procedimiento), concentración de hemoglobina eritrocítica corpuscular media, determinación de concentración hemoglobínica corpuscular media, SAI, concentración de hemoglobina corpuscular media de los eritrocitos, determinación de concentración de hemoglobina corpuscular media, SAI, CHCM, MCHC, determinación de concentración de hemoglobina corpuscular media, SAI (hallazgo), concentración de hemoglobina corpuscular media, concentración de hemoglobina corpuscular media de los glóbulos rojos, MCHC - NOS, determinación de la CHCM, determinación de la concentración de hemoglobina corpuscular media (procedimiento), determinación de la concentración de hemoglobina corpuscular media, Concentración de hemoglobina corpuscular media, determinación de CHCM
Norwegian Middelcellehemoglobinkonsentrasjon, MCHC