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Leukocyte Morphology on Peripheral SmearAka: Leukocyte Morphology, Plasmablast, Myeloblast, Promyelocyte, Myelocyte, White blood Cell morphology, Hypersegmented Neutrophil, Bilobed Neutrophil, Atypical lymphocyte, Toxic granulation, Lymphoblast
- See Also
- Bone Marrow Exam
- Leukocyte
- Background
- Variants below as seen on Peripheral Smear
- Toxic granulation of Neutrophils and Metamyelocytes
- Bacterial infections
- Atypical Lymphocytes
- Viral infections
- Giant cytoplasmic granules
- Chediak-Higashi Syndrome
- Bilobed Neutrophils
- Pelger-Huet anomaly
- Hypersegmented Neutrophils
- Pernicious Anemia (Vitamin B12 Deficiency)
- Folate Deficiency
- Myeloproliferative disease
- Myeloblasts, Promyelocytes, Myelocytes
- Acute myeloblastic Leukemia
- Acute promyelocytic Leukemia
- Chronic myelocytic Leukemia
- Myelofibrosis
- Polycythemia Vera
- Large granular Lymphocytes
- T-gamma lymphoproliferative disease
- Natural Killer Cells
- Lymphoblasts
- Acute lymphoblastic Leukemia
- Prolymphocytic Leukemia
- Malignant Lymphoma
- Chronic Lymphocytic Leukemia
- Infectious Mononucleosis
- Plasmablasts
- Multiple Myeloma
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| Definition (NCI) | A cell of the bone marrow that is derived from myeloblasts and will give rise to myelocytes, precursors of myeloid cells and neutrophil granulocytes. |
| Definition (MSH) | The cells in the granulocytic series that are derived from myeloblasts and that are the earliest cells of the myelocyte stage. |
| Concepts | Cell (T025)
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| English | Premyelocyte, Premyelocytes, Progranulocyte, Progranulocytes, Promyelocyte, Promyelocytes |
| Spanish | progranulocito, promielocito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Atypical lymphocyte (C0221277)
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| Concepts | Cell (T025)
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| English | Abnormal Lymphocyte, Atypical lymphocyte, Atypical lymphocytes, LYMPHOCYTES ATYPICAL, Lymphocytes.abnormal, Lymphocytes.atypical, Reactive Lymphocyte |
| Spanish | linfocito atÃpico, linfocito atipico, linfocito reactivo |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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| Definition (CSP) | a morphologically immature lymphocyte, once thought to represent an early stage in lymphocyte development but now known to be an activated lymphocyte that has been transformed in response to antigenic stimulation. |
| Definition (NCI) | An immature lymphocyte that has enlarged in response to antigenic stimulation. |
| Concepts | Cell (T025)
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| English | lymphoblast, Lymphoblasts, Lymphocytoblast |
| Spanish | linfoblasto, linfocitoblasto |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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| Definition (NCI) | An immature cell that represents the first stage in the granulocytic series of hematopoiesis. It is found in bone marrow and differentiates into a promyelocyte. Its nucleus is composed of very fine, evenly distributed chromatin with 2-5 nucleoli. The cytoplasm is basophilic and non-granular. |
| Concepts | Cell (T025)
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| English | myeloblast, Myeloblasts |
| Spanish | mieloblasto |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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| Definition (CSP) | precursor in the granulocytic series; in this stage, differentiation into specific cytoplasmic granules has begun. |
| Definition (NCI) | A cell derived from a promyelocyte. It differentiates into a metamyelocyte. It has a diameter of 10-18 micrometer, and an oval or round nucleus with finely granulated chromatin. |
| Concepts | Cell (T025)
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| English | Myelocyte, Myelocytes |
| Spanish | mielocito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Hypersegmented neutrophil (C0483202)
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| Concepts | Cell or Molecular Dysfunction (T049)
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| English | Hypersegmented neutrophil, Neutrophils.hypersegmented |
| Spanish | neutrófilo hipersegmentado, neutrofilo hipersegmentado |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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