Hematology and Oncology Book

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Haptoglobin

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  1. Normal
    1. Range: 50-220 mg/dl
    2. Acute phase reactant
  2. Increased
    1. Inflammation
    2. Collagen-Vascular Disease
    3. Infection
    4. Androgens
  3. Decreased
    1. Hemolysis (intravascular)
    2. Megaloblastic Anemia
    3. Severe liver disease
    4. Large hematomas
    5. Epstein Bar Virus (EBV)
    6. Cytomegalovirus
    7. Oral Contraceptives

Haptoglobins (C0018595)

Definition (MSH)Plasma glycoproteins that form a stable complex with hemoglobin to aid the recycling of heme iron. They are encoded in man by a gene on the short arm of chromosome 16.
Definition (CSP)a blood glycoprotein found in the alpha globulin fraction which binds free hemoglobin.
ConceptsAmino Acid, Peptide, or Protein (T116) , Biologically Active Substance (T123)
EnglishHaptoglobin, Haptoglobins
Spanishhaptoglobina
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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